Caldwell B. Esselstyn, Jr., MD, F.A.C.S.

Born  New York City, New York, December 12, 1933

A.B. Yale University, 1956 MD, Western Reserve University School of
Medicine, 1961

Intern, Cleveland Clinic Hospital, 1961-1962
Resident, General Surgery, Cleveland Clinic Hospital, 1962-1966

Senior Registrar with Professor Bryan Brooke, St. George Hospital,
London, England, March 1965 – September 1965

Captain United States Medical Corps, 1966-1968
United States Army Hospital, Fort Bragg, North Carolina, 1966-1967
Third Field Hospital, Saigon, Vietnam, 1967-1968
Second Surgical Hospital Chu Lai, Vietnam, 1968

Staff, Cleveland Clinic Foundation, Department of General Surgery,
1968 – 2006   Former Head, Section of Thyroid and Parathyroid Surgery,
Former Chairman Breast Cancer Task Force

Licenses and Certificates

Michigan Basic Science Certificate
Certificate of the National Board of Medical Examiners
Ohio State License
New York State License

Society Memberships

Diplomate, American Board of Surgery Fellow
American College of Surgeons
American Medical Association
Board of Directors, Rip Van Winkle Foundation
Cleveland Surgical Association
Cleveland Academy of Medicine
Collegium Internationale Chirugiae Digestive
Eastern Surgical Society
International Association of Endocrine Surgeons
Pan Pacific surgical Association
Societe Internationale De Chirurgiae
Society of Surgical Oncology
Society of Head and Neck Surgeons
Surgeons Travcl Club
Society of Head and Neck Surgeons

Honors

Member of the 1956 United States Olympic Team, awarded Gold Medal in 8-Oared Rowing Event
President – Nu Sigma Nu Medical Fraternity, 1960 .
Bronze Star, Vietnam Campaign, May 1968
President – Cleveland Surgical Society, 1983
President – Medical Staff Cleveland Clinic Foundation, 1977-78
Member of the Board of Trustees, Cleveland Clinic Foundation, 1981-1983
Member of Board of Governors, Cleveland Clinic Foundation, 1979-1984
President – Rupert Turnbull Society, 1982-1983
President – Cleveland Clinic Surgical Society, 1984
Member of the Board of Trustees of the Medical Alumni Association of Case Western Reserve University, 1981-1984
Kiphuth Fellow Award, Yale University, 1982
Vice President – American Association of Endocrine Surgeons – 1988-89
President-elect – American Association of Endocrine Surgeons – 1989-90
Chairman, Constitution By-Laws Committee – Society of Surgical Oncology 1989-1990
Chairman, Breast Cancer Task Force – Cleveland Clinic Foundation
Chairman, Membership Committee – Surgeons’ Travel Club
President, American Association of Endocrine Surgeons – 1990-91
Chairman and Program Director – 1st National Conference on the Elimination of Coronary Artery Disease – Tucson, Arizona – October, 1991.
Listed in Best Doctors in America 1994-95 – Endocrine Surgery, Pg. 156: Surgical Oncology, Breast Cancer, Pg. 857.
Chairman and Program Director – Summit on Cholesterol & Coronary Disease – 2nd National Conference on Lipids in the Elimination and Prevention of Coronary Artery Disease – Orlando, Florida – September  4-5, 1997
Member of the Scientific Advisory Board of the Nutrition Action Healthletter (CSPI – Center for Science in the Public Interest) 1997.
First Recipient of the  Benjamin Spock Award for Compassion in Medicine  2005
Cleveland Heart Lab 2012 Heart Award for lifelong dedication to the prevention of chronic disease
First Recipient of the  2013 Deerfield Academy Alumni Association Heritage Award In Recognition of Outstanding Achievement & Service

 

T. Colin Campbell
Education:
1956 Penn State University B.S. Pre-veterinary
1957 Cornell University M.S. Nutrition, Biochemistry
1962 Cornell University Ph.D. Nutrition, Biochemistry
Bacteriology
Societies and Honors:
American Society for Nutritional Sciences (FASEB)
International Nutrition Society
American Society of Pharmacology and Experimental Therapeutics
(FASEB)
Society of Toxicology
Sigma Xi
NIH Research Career Development Award (1974-1976)
American Society for Clinical Nutrition Visiting Professorship to
the University of Maryland Medical School at Baltimore (1980)
National Cancer Institute Exchange Scholar to the Peoples Republic
of China (1981)
Sam E. and Mary F. Roberts Foundation Awardee (1988)
Distinguished Lecturer, Taiwan Nutrition Society (1991)
Research featured on cover of Journal of National Cancer Institute
(1985) and Cancer Research (1991)
Exemplary Commitment of Excellence, Western-Ellington Alumni
Association (1992)
“Hero” of Food & Nutrition, Eating Well Magazine (1994)
Recipient, First Prize for Most Outstanding Publication in
Preventive Medicine in China for 20 Years, 1976-1996
Listed as one of Top 25 Food Influentials, Self, 1998
JADE Chopsticks Award for Outstanding Chinese Nutrition Research,
1997
Giraffe Commendation (for “outrageous actions for the common
good”), 1998
Green College Scholar, University of Oxford, UK
1998 American Institute for Cancer Research Award “in
recognition of a lifetime of significant accomplishments in
scientific research and his efforts in furthering scientific
knowledge and understanding in diet, nutrition and cancer
AAUP Heikkila Memorial Lecture, New Jersey Medical School and
Robert Wood Johnson Medical School Lectures, 2003
2004 Burton-Kallman Scientific Achievement Award, National
Nutritional Foods Association
Professional positions:
1985-present Jacob Gould Schurman Professor Emeritus of
Nutritional Biochemistry, Cornell University,
Ithaca, New York
2
1991-present Honorary Professor, Chinese Academy of Preventive
Medicine
1983-present Director, Nutrition and Cancer Program Project
(Collaborative Project with Chinese Academy of
Preventative Medicine, Chinese Academy of Medical
Sciences/China Cancer Institute, and University of
Oxford)
1992-1997 Senior Science Advisor, World Cancer Research Fund
and American Institute for Cancer Research
1994-1997 Organizer and Co-Chair, Expert Panel, Dietary
Prevention of Cancer Worldwide
1985-1986 Visiting Scholar, Green College, University of
Oxford, Oxford, England
1975-1985 Professor of Nutritional Biochemistry, Cornell
University, Ithaca, New York
1983-1987 Senior Science Advisor, American Institute for
Cancer Research, Falls Church, Virginia
1978-1979 Senior Scientific Consultant, Life Sciences Research
Office, FASEB, Bethesda, Maryland (Sabbatical leave)
1974-1975 Professor of Biochemistry and Nutrition, VPR&SU,
Blacksburg, Virginia
1968-1974 University Coordinator of Philippine Programs,
VPI&SU, Blacksburg, Virginia
1969-1974 Associate Professor of Biochemistry and Nutrition,
VPI&SU Blacksburg, Virginia
1965-1969 Assistant Professor of Biochemistry and Nutrition,
VPI&SU Blacksburg, Virginia
1963-1965 Research Associate, Massachusetts Institute of
Technology Cambridge, Massachusetts
1961-1963 Senior Chemist, Woodard Research Corporation
Herndon, Virginia
1957-1958 Scientist, Hazelton Laboratories, Inc.
Research Interests:
Relationship of diet, nutrition and chronic degenerative disease
etiology; nutritional effects on carcinogen and foreign
compound metabolism; aflatoxin/liver cancer relationships;
risk assessment and chemical toxicity.
Publications & Presentations (325+)
3
Legend: * Books
** Reviews
*** Manuscripts
# Abstracts
+ Presentations
***1. Campbell, T.C., Warner, R. G. and Loosli, J.K. Urea and
biuret for ruminants. Proc., Cornell Nutr. Conf., p. 96.
1960.
***2. Campbell, T.C., Loosli, J.K., Warner, R.G. and Tasaki, I.
Utilization of biuret by ruminants. J. An. Sci. 22:139, 1963.
#3. Campbell, T.C. and Fieldman, L. Metabolism of chick edema
factor. Fed. Proc. 24:686 Abs, 1965.
+4. Campbell, T.C. Mycotoxins in the Food Chain, Virginia Academy
of Science, Harrisonburg, Va., May 5, 1966.
***5. Campbell, T.C. and Friedman, L. Chemical assay and isolation
of chick edema factor in biological materials. JAOAC 49:824,
1966.
***6. Campbell, T.C. and Friedman, L. Chick edema factor: Some
tissue distribution data and toxicologic effects in the rat
and chick. Proc. Soc. Exp. Biol. Med. 121:1283, 1966.
+7. Campbell, T.C. Aflatoxin as an Important Feed Contaminant,
National Association of Feed Manufacturers, Washington, D.C.,
May 8, 1967.
+8. Campbell, T.C. Influence of Environmental Factors on
Mycotoxin Toxicity as Evidenced by Studies with Aflatoxin,
National Meetings, American Veterinary Medical Association,
Detroit, Michigan, June 20, 1967.
**9. Campbell, T.C. Invitational Paper: “Significance of
Mycotoxins in the Food Chain”. Va. J. Sci. 18:67, 1967.
***10. Campbell, T.C. Present day knowledge on aflatoxin. Phil. J.
Nutr. 20: 193-201, 1967.
***11. Campbell, T.C. and Snider, J. Noninterference of seed coat
constituents of cottonseeds using the Pons and Goldblatt
aflatoxin procedures. J.Am. Oil Chem. Soc. 46:31-33, 1968.
#12. Gurtoo, H., Campbell, T.C., Webb, R.E. and Plowman, K.M.
Effects of aflatoxin and benzpyrene on microsomal
hydroxylation. Fed. Proc. 27:551 Abs., 1968.
***13. Gurtoo, H.L., Campbell, T.C., Webb, R.E. and Plowman, K.M.
Effect of aflatoxin and benzpyrene pretreatment upon the
4
kinetics of benzpyrene hydroxylase. Biochem. Biophys. Res.
Comm. 31:588, 1968.
***14. Hanna, K.L. and Campbell, T.C. A rapid thin layer
chromatographic method for the preparation of aflatoxin B1.
JAOAC 51:1197-1199, 1968.
***15. Portman, R., Campbell, T.C. and Plowman, K.M. Aflatoxin
metabolism by liver microsomal preparations of two different
species. Biochem. Biophys. Res. Comm. 33:711-715, 1968.
#16. Portman, R., Campbell, T.C. and Plowman, K.M. Metabolic
mechanisms affecting aflatoxin B1 toxicity in two species.
Fed. Proc. 27:839 Abs., 1968.
#17. Weatherholtz, W.M., Campbell, T.C. and Webb, R.E. Effects of
dietary protein level on acute toxicity and metabolism of
heptachlor in the laboratory rat. Fed Proc. 27:551 Abs., 1968.
***18. Baugher, W.L. and Campbell, T.C. Gossypol detoxification by
fungi. Science 164:1526-1527, 1969.
***19. Marsh, P.B., Simpson, M.E., Ferretti, R.J., Campbell, T.C. and
Donoso, J. Aflatoxins in cottonseeds at harvest. I. Relation
to fluorescence in the fiber. J. Ag. Food Chem. 17:462-467,
1969.
***20. Weatherholtz, W.M.. and Campbell, T.C. and Webb, R.E. Effect
of dietary protein levels on the toxicity and metabolism of
heptachlor. J. Nutr. 98:90-94, 1969.
***21. Wilson, B.J., Campbell, T.C., Hayes, A.W. and Hanlin, R.T.
Investigation of reported aflatoxin production by fungi
outside the Aspergillus flavus group. Appl. Microbiol. 16:819,
1969.
#22. Campbell, T.C. and Portman, R.S. Aflatoxin metabolism in the
rat and mouse liver. Fed. Proc. 29:567 Abs., 1970.
***23. Campbell, T.C., Caedo, J.P., Jr., Bulatao-Jayme, J., Salamat,
L. and Engel, R.W. Aflatoxin M1 in human urine. Nature
227:403-404, 1970.
***24. Gurtoo, H.L. and Campbell, T.C. A kinetic approach to a study
of the induction of rat liver microsomal hydroxylase after
pretreatment with 3,4-benzpyrene and aflatoxin B1. Biochem.
Pharmacol. 19:1729-1735, 1970.
***25. Portman, R.S. and Campbell, T.C. In vitro inhibition of E.
coli RNA polymerase transcription of rat liver chromatin by
aflatoxin B1. Biochem. Biophys. Res. Comm. 41:774-780, 1970.
5
***26 Portman, R.S., Plowman, K.M. and Campbell, T.C. On mechanisms
affecting species susceptibility to aflatoxin. Biochem.
Biophys. Acta 208:487-495, 1970.
***27. Campbell, T.C. and Salamat, L. Aflatoxin ingestion and
excretion by humans. In: Mycotoxins in Human Health, Purchase,
I.F. (ed.) London: MacMillan Press, Ltd., pp. 271-280. 1971.
***28. Campbell, T.C. Detoxification of gossypol by Eumycophyta,
Patent No. 3,682,645, August 8, 1972.
+29. Campbell, T.C. Implications of Mycotoxins for Human Health,
Symposium on Potentially Toxic Substances in Human Foods,
Ninth International Congress of Nutrition Mexico City, Mexico,
September 9, 1972.
#30. Doherty, W.P. and Campbell, T.C. Effect of aflatoxin B1 on
rat liver mitochondrial electron transport. Fed. Proc. 31:594
Abs., 1972.
***31. Doherty, W.P. and Campbell, T.C. Inhibition of rat liver
mitochondrial electron transport flow by aflatoxin B1. Res.
Comm. Chem. Pathol. Pharmacol. 3:601-612, 1972.
#32. Hayes, J.R., Mgbodile, M.U.K. and Campbell, T.C. Effect of
protein deficiency on inducibility of the rat liver microsomal
drug-metabolizing system. Fed. Proc. 31:734 Abs., 1972.
***33. Kornegay, E.T., Kelly, R.F., Campbell, T.C., Libke, K.G.,
Sandrock, R.W. and Blair, J.E. Fungal treated cottonseed meal
for swine. J. Nutr. 102:1471-1476, 1972.
#34. Mgbodile, M.U.K. and Campbell, T.C. Alterations in the
kinetic parameters of types I and II microsomal enzyme
activities in male rats following protein and energy
deprivation. Fed. Proc. 30:440 Abs., 1972.
***35. Mgbodile, M.U.K. and Campbell, T.C. Effect of protein
deprivation of male weanling rats on the kinetics of hepatic
microsomal enzyme activity. J. Nutr. 102:53-60, 1972.
#36. Mgbodile, M.U.K., Merrill, A.H. and Campbell, T.C. Timecourse
effects of dietary protein levels on liver microsomal
protein and liver DNA of growing rats. Fed. Proc. 31:729 Abs.,
1972.
#37. Belt, J.A. and Campbell, T.C. Effect of aflatoxin B1 on
mitochondrial incorporation of UTP. Fed. Proc. 32:277 Abs.,
1973.
***38. Campbell, T.C., Caedo, J.P., Jr., Bulatao-Jayme, J., Salamat,
L. and Engel, R.W. Aflatoxin M1 in human urine. In: Chemical
and Radio-nuclide Food Contamination, Alpert, M.E. et al.
(eds.). New York: MSS Information Corp., pp. 18-22. 1973.
6
+39. Campbell, T.C. Nutritional Factors in Toxin Response,
Symposium on Environmental Pharmacology and Toxicology,
American Society for Pharmacology and Experimental
Therapeutics, East Lansing, Michigan, August 20, 1973.
***40. Doherty, W.P. and Campbell, T.C. Aflatoxin inhibition of rat
liver mitochondria. Chem.-Biol. Int. 7:63-77, 1973.
#41. Doherty, W.P. and Campbell, T.C. The effect of aflatoxin B1
on electron-transport in submitochondrial particles. Fed.
Proc. 32:278 Abs., 1973.
#42. Effect of Nutrient Intake on Toxin Metabolism, Workshop on
Pharmacology, Toxicology, and Nutrition Interactions, American
Institute of Nutrition, Ithaca, New York, August 15, 1973.
#43. Gurtoo, H.L. and Campbell, T.C. Interaction of aflatoxin and
their metabolites with rat liver microsomes. Proc. Intl.
Congress Hepatotoxicity. Tel Aviv, Israel. 1973.
#44. Hayes, J.R. and Campbell, T.C. Effect of protein deficiency
on 3-methylcholanthrene (MC) induction of rat liver microsomal
drug-metabolizing system. Fed. Proc. 32:716 Abs, 1973.
***45. Hayes, J.R., Mgbodile, M.U.K. and Campbell, T.C. Dependence
of Km and Vmax on substrate concentration for rat liver
hepatic microsomal ethylmorphine N-demethylase. Biochem.
Pharmacol. 22:1517-1520, 1973.
***46. Hayes, J.R., Mgbodile, M.U.K. and Campbell, T.C. Effect of
protein deficiency on the inducibility of the hepatic
microsomal drug-metabolizing enzyme system. I. Effect on
substrate interaction with cytochrome P450. Biochem.
Pharmacol. 22:1005-1014, 1973.
***47 Merrill, A.H., Jr. and Campbell, T.C. Preliminary study of in
vitro aflatoxin B1 metabolism by human liver. J. Tox. Appl.
Pharmacol. 27:210-213, 1973.
***48. Mgbodile, M.U.K., Hayes, J.R. and Campbell, T.C. Effect of
protein deficiency on the inducibility of the hepatic
microsomal drug-metabolizing enzyme system. II. Effect on
enzyme kinetics and electron transport system. Biochem.
Pharmacol. 22:1125-1132, 1973.
**49. Campbell, T.C. and Stoloff, L. Implications of mycotoxins for
human health. J. Agr. Food Chem. 22:1006-1015, 1974.
**50. Campbell, T.C. and Hayes, J.R. Role of nutrition in the drug
metabolizing enzyme system. Pharm. Revs. 26:171-197, 1974.
***51. Campbell, T.C., Sinnhuber, R.O., Lee, D.J. and Salamat, L.
Hepatocarcinogenic material in urine specimens from humans
consuming aflatoxin. J. Natl. Cancer Inst. 52:1647-1649,
1974.
7
+52. Campbell, T.C. The Effect of Diet on Drugs and Environmental
Toxins, Seventh Vitamin Information Bureau Seminar for Editors
and Writers on Nutrition and National Priorities, New York
City, November 7, 1974.
***53. Gurtoo, H.L. and Campbell, T.C. Metabolism of aflatoxin B1
and metabolism dependent and independent binding of aflatoxin
B1 to rat hepatic microsomes. Mol. Pharmacol. 10:776-780,
1974.
#54. Hayes, J.R., Hartgrove, R.W., Hundley, S.G., Campbell, T.C.
and Webb, R.E. Interaction of endrin and dieldrin with
hepatic microsomal cytochrome P-450. J.Tox. Appl. Pharmacol.,
89:126 Abs., 1974.
***55. Hayes, J.R. Mgbodile, M.U.K. and Campbell, T.C. Effect of
protein deficiency on the inducibility of the hepatic
microsomal drug-metabolizing enzyme system. III. Effect of 3-
methylcholanthrene induction on activity and binding kinetics.
Biochem. Pharmacol. 23:1721-1732, 1974.
#56. Merrill, A.H., Jr., Salamat, L. and Campbell, T.C. Studies on
the excretion of aflatoxin and its derivatives by humans. J.
Tox. Appl. Pharmacol., 89:94 Abs., 1974.
#57. Nerurkar, L.S. and Campbell, T.C. Metabolism of aflatoxin B1
by an intact and reconstituted rat liver microsomal enzyme
system. J. Tox. Appl. Pharmacol., 29:89 Abs, 1974.
***58. Polan, C.E., Hayes, J.R. and Campbell, T.C. Consumption and
fate of aflatoxin B1 in lactating cows. J. Agr. Food Chem.
22:635-638, 1974.
#59. Belt, J.A. and Campbell, T.C. Effect of aflatoxin on
mitochondrial protein synthesis. Fed. Proc. 34:226 Abs., 1975.
**60. Campbell, T.C. and Hayes, J.R. The liver microsomal system
and mycotoxin metabolism. Microbiology, 1975, pp. 372-380.
1975.
+61. Campbell, T.C. Protein Deficiency and Mixed Function Oxidase
Activities, Joint AIN ASPET Symposium on Nutrition and Drug
Metabolism, Atlantic City, New Jersey, April, 1975.
+62. Campbell, T.C. The Liver Microsomal System and Mycotoxin
Metabolism, American Society of Microbiology Symposium on
Biochemical Effects and Interactions of Mycotoxins, New York
City, April, 1975.
**63. Campbell, T.C. Effect of dietary protein on drug metabolism.
Metab. Ther., 4(4):Winter, 1975.
#64. Fairclough, D.L., Fox, J.P. and Campbell, T.C. Effect of
aflatoxin preincubation and addition to rat liver microsomes
8
on mixed function oxidase activity. Fed. Proc. 34:784 Abs.,
1975.
***65. Hayes, J.R., Hartgrove, R.W., Hundley, S.G., Campbell, T.C.
and Webb, R.E. Interaction of endrin and dieldrin with
hepatic microsomal cytochrome P450 from the rat, mouse, and
endrin susceptible and resistant pine voles. J. Tox. Appl.
Pharmacol. 32:559-565, 1975.
***66. Stoloff, L., Trucksess, M., Hardin, N., Francis, O.J., Hayes,
J.R., Polan, C.E. and Campbell, T.C. Studies on the stability
of aflatoxin M in milk. J. Dairy Sci. 58:1789-1793, 1975.
+67. Aflatoxin Metabolism as it Relates to its Biological Activity,
National Institute of Environmental Sciences Workshop on
Mutagenesis-Drug Metabolism, Research Triangle Park, Research
Triangle, North Carolina, February 8, 1976.
***68. Campbell, T.C. Aflatoxin metabolism. In: In Vitro Metabolic
Activation in Mutagenesis Testing, de Serres, F.J., Fouts,
J.R., Bend, J.R., and Philpot, R.M. (eds.). New York: North-
Holland Publishing Company, pp. 243-xxxx. 1976.
**69. Campbell, T.C. and Hayes, J.R. The effect of quantity and
quality in dietary protein on drug metabolism. Fed. Proc.
35:2470-2474, 1976.
**70. Campbell, T.C. and Hayes, J.R. The role of aflatoxin
metabolism in its toxic lesion. Tox. Appl. Pharm. 35:199-222,
1976.
**71. Campbell, T.C. Modern concepts in nutritional status and
foreign compound toxicity. In: Advances in Modern Toxicology
– Newer Concepts in Safety Evaluation, Mehlman, M.A.,
Blumenthal, H. and Shapiro, R. (eds.). New York: Academic
Press, pp. 1131. 1976.
+72. Campbell, T.C. Effects of Dietary Protein on Drug Metabolism,
International Symposium on Nutrition and Drug Interrelations,
Ames, Iowa, August 5, 1976.
+73. Campbell, T.C. Effects of Nutritional Status on Drug
Metabolism Symposium on Nutrient-drug Interaction at Meharry
Medical College, Nashville, Tennessee, February 27, 1976.
+74. Campbell, T.C. Nutrition and Drug Metabolizing Enzymes,
Fourth Deer Lodge Conference on Clinical Pharmacology, Big
Fork, Montana, September 7, 1976.
+75. Campbell, T.C. Nutrition and Drug Metabolism, Program on
Perspectives in Nutrition, Ithaca, New York, June 2, 1976.
***76. Preston, R.S., Hayes, J.R. and Campbell, T.C. The effect of
protein deficiency on the in vivo binding of aflatoxin B1 to
rat liver macromolecules. Life Sci. 19:1191-1198, 1976.
9
#77. Allen-Hoffman, B.L. and Campbell, T.C. The relationship
between hepatic glutathione levels and the formation of
aflatoxin B1-DNA adducts as influenced by dietary protein
intake. Fed. Proc. 36:1116 Abs., 1977.
+78. Campbell, T.C. Aflatoxin toxicity and carcinogenicity, Gordon
Research Conference. 1977.
+79. Campbell, T.C. Drug Metabolizing Enzymes as Affected by
Nutritional Status, Western Hemisphere Nutrition Congress V,
Quebec, Canada, August 15, 1977.
**80. Campbell, T.C. Nutrition and Drug-Metabolizing Enzymes. Clin.
Pharm. Therap. 22:699-706, 1977.
+81 Campbell, T.C. Role of nutrition in carcinogen metabolism.
Gordon Research Conference, 1977.
+82. Campbell, T.C. The Influence of Dietary Factors on Drug
Metabolism in Animals, Drug Metabolism Reviews, Sarasota,
Florida, November 7, 1977.
#83. Hayes, J.R., Polan, C.E., Campbell, T.C. Bovine liver
metabolism and tissue distribution of alfatoxin B1. J. Agr.
Food Chem. 25:xxxxxx, 1977.
***84. Adekunle, A.A., Hayes, J.R. and Campbell, T.C.
Interrelationships of dietary protein level, aflatoxin B1
metabolism, and hepatic microsomal expoxide hydrase activity.
Life Sci. 21:1785-1792, 1978.
**85. Campbell, T.C. Effects of dietary protein on drug metabolism.
In: Nutr. Fedn. Monograph, Hathcock, J.N. and Coon, J.M.
(eds.). New York: Academic Press, Chap. 15, pp. 409-422. 1978.
***86. Campbell, T.C., Hayes, J.R. and Newberne, P.M. Dietary
lipotropes, hepatic microsomal mixed function oxidase
activities, and in vivo covalent binding of aflatoxin B1 in
rats. Cancer Res. 38:4567-4571, 1978.
**87. Campbell, T.C. Role of metabolic studies in evaluation of
mycotoxin health risks. In: Mycotoxins in Human and Animal
Health, Rodricks, J.V., Hesseltine, C.W. and Mehlman, M.A.
(eds.). Park Forest South, Ill.: Pathotox Publishers, Inc.,
pp. 687-698. 1978.
***88. Campbell, T.C. Saccharin, Cancer, and calories. (Letter to
editor). Science 202:260-261, 1978.
#89. Falahee, K.J. and Campbell, T.C. The effect of dietary
protein level on the in vivo covalent binding of dibenz(a,h)
anthracene (DBA) to hepatic and lung DNA as a function of
pretreatment with MFO modifiers. Fed. Proc. 37, xxxx Abs.,
1978.
10
#90. Hayes, J.R. and Campbell, T.C. Time course alternations in
the covalent binding of AFB1 to liver macromolecules of rats
and mice. Pharmacologist, 20:xxxx Abs., 1978.
***91. Hayes, J.R., Mgbodile, M.U.K., Merrill, A.H., Jr., Nerurkar,
L.S. and Campbell, T.C. The effect of dietary protein
depletion and repletion on rat hepatic mixed function oxidase
activities. J. Nutr. 108:1788-1797, 1978.
***92. Nerurkar, L.S., Hayes, J.R. and Campbell, T.C. The
reconstitution of hepatic microsomal mixed funtion oxidase
activity with fractions derived from weanling rats fed
different levels of protein. J. Nutr. 108:678-686, 1978.
+93. Campbell, T.C. Testimony on “Chemical Carcinogens in the
Laboratory Workplace”, OSHA Hearings, Washington, D.C., June
20, 1978.
+94. Numerous seminars and presentations on “Diet, Nutrition and
Cancer”, “Nutritional Toxicology,” etc., to universities and
public groups, 1978-1985 (6-10 per year).
*95. Rosenblith, W.A., Grobstein, C., Abelson, R.P., Campbell,
T.C., Harris, J.L., LaDu, B.N., Jr., Miller, R.W., Nelson,
H.E., Price, D.K., Rosen, S., Shapo, M.S., Williamson, O.E.
and Winikoff, B. Food Safety Regulations and Societal Impact,
Report of a Study on Food Safety Policy, Scientific and
Societal Considerations. U.S. National Academy of Sciences,
National Research Council March 1978.
*96. Abramson, F.P., Campbell, T.C., McCann, J., Nelson, H.E.,
Samuels, S.W. Minority statement to report by Rosenblith et
al.. (supra vide). 1979.
#97. Allen-Hoffmann, B.L. and Campbell, T.C. Effect of
phenobarbital and diethyl maleate pretreatment on covalent
binding of 3H-AFB1 to hepatic macromolecules. Fed. Proc.
38:865 Abs., 1979.
**98. Campbell, T.C. Influence of Nutrition on Metabolism of
Carcinogens. In: Adv. Nutr. Res., II. Draper, H. H. (ed.) New
York: Plenum Press, pp. 29-55. 1979.
**98a. Campbell TC Hayes JR Merrill AH Maso M Goetchius M. The
influence of dietary factors on drug metabolism in animals.
Drug Metabolism Reviews 9:173-184, 1979.
+99. Campbell, T.C. How Toxic is Toxic–A Commentary, New York
City Food Policy Conference, New York, NY, March 14, 1979.
#100. Falahee, K.J. and Campbell, T.C. The influence of dietary
protein level and 7,8-benzoflavone on the in vivo covalent
binding of benz(a)pyrene to liver and lung DNA. Fed. Proc.
38:369 Abs., 1979.
11
#101. Hayes, J.R. and Campbell, T.C. Alterations in covalent
binding of aflatoxin B1 to liver macromolecules as influenced
by route of administration. J. Tox. Appl. Pharmacol., 48:16
Abs., 1979.
#102. Hayes, J.R. and Campbell, T.C. In vivo covalent binding of
aflatoxin B1 (AFB1) to DNA by rats and mice as a function of
dose size. Fed. Proc. 38:534 Abs., 1979.
#103. Mainigi, K.D. and Campbell, T.C. Carcinogen-macromolecular
adducts in liver subcellular fractions during aflatoxin (AFB1)
feeding. AACR Proc. 20:201 Abs., 1979.
#104. Mainigi, K.D. and Campbell, T.C. The effect of dietary
protein on the subcellular distribution and binding of
aflatoxin in rat liver. J. Tox. Appl. Pharmacol., 48:150,
1979.
**105. Allison, R. G., Carr, C.J. and Campbell, T.C. Guidelines for
Safety Evaluation of Nutrients. Prepared for Food and Drug
Administration, Washington, D.C., under Contract No. FDA 223-
75-2090 by the Life Sciences Research Office, FASEB, Bethesda,
MD. 1980.
**106. Campbell, T.C., Allison, R.G. and Carr, C.J. Feasibility of
Identifying Adverse Health Effects of Vitamins and Essential
Minerals in Man. Prepared for Food and Drug Administration,
Washington, D.C., under Contract No. FDA 223-75-2090 by the
Life Sciences Research Office, FASEB, Bethesda, MD. 1980.
**107. Campbell, T.C. Chemical Carcinogens and Human Risk
Assessment. Fed. Proc. 39:2467-2484, 1980.
***108. Campbell, T.C. LSRO reports as models. Fed. Proc. 39:121-
122, 1980.
**109. Hayes, J.R. and Campbell, T.C. Nutrition as a modifier of
chemical carcinogenesis. In: Carcinogenesis, Vol. 5:
Modifiers of Chemical Carcinogenesis, Slaga, T.J. (ed.) New
York: Raven Press, pp. 207-241. 1980.
**110. How Toxic is Toxic? Cooperative Extension of Erie County
Nutrition Conference, Grand Island, NY, May 13, 1980.
+111. Keynote Address: The Safety of the Food Supply–
Underdiscussed Issues, Biennial Nutrition Institute, “Toward a
National Nutrition Policy,” Cornell University, Ithaca, NY,
June 5, 1980.
#112. Mainigi, K.D. and Campbell, T.C. Effect of steroid hormones
on the incorporation and binding of aflatoxin (AFB1) in rat
liver cytosol, microsomes and nuclei. AACR Proc. 21:498 Abs.,
1980.
12
***113. Mainigi, K.D. and Campbell, T.C. Subcellular distribution and
covalent binding of aflatoxins as functions of dietary
manipulation. J. Tox. Environ. Health 6:659-671, 1980.
#114. Appleton, B.S. and Campbell, T.C. Effects of dietary protein
level and phenobarbital on aflatoxin-induced hepatic aglutamyl
transpeptidase in the rat. Fed. Proc. 40:3477 Abs.,
1981.
#115. Boyd, J.N., Misslbeck, N., Campbell, T.C., Babish, J.C. and
Stoewsand, G.S. Application to benzo(a)pyrene fed rats of a
proposed short-term in vivo carcinogen screening protocol. J.
Tox. Appl. Pharmacol. 1:131 Abs., 1981.
***116. Boyd, J.N., Misslbeck, N., Babish, J.G., Campbell, T.C. and
Stoewsand, G.S. Plasma alphafetoprotein elevation and
mutagenicity of urine as early predictors of carcinogenicity
in benzo(a)pyrene fed rats. Drug Chem. Tox. 4:197-205, 1981.
***117. Boyd, J.N., Stoewsand, G.S., Misslbeck, N., Campbell, T.C.,
Mason, R., Lepp, A. and Odstrchel, G. Enhancement of plasma
a-fetoprotein, as measured by sandwich-type radioimmunoassay,
and induction of g-glytamyl transpeptidase-positive hepatic
cell foci in rats fed benzo(a) pyrene. J. Tox. Environ.
Health 7:1025-1035, 1981.
***118. Campbell, T.C. A decision tree approach to the regulation of
food chemicals associated with irreversible toxicities.
Regulatory Tox. Pharm. 1:193-201, 1981.
**119. Campbell, T.C., Allison, R.G. and Fisher, K.D. Nutrient
Toxicity. Nutr. Revs. 39:249-256, 1981.
+120. Campbell, T.C. Five lectures on environmental carcinogenesis,
cancer risk assessment and diet and cancer. Chinese Academy
of Medical Sciences and Beijing Cancer Institute, Beijing,
China, Oct. 1-14, 1981.
**121. Campbell, T.C. More is not necessarily better. Natural
History, 90:12-16, 1981.
*122. Campbell, T.C. Nutrition Primer: What About the Food You Eat?
Carolina-Biological Supply/Oxford University Press. Summer
1981. (designed for secondary school system).
+123. Campbell, T.C. The Diet, Nutrition and Cancer Web. Career
Teaching Day, The American Cancer Society of Onondaga County.
Syracuse, NY, November 4, 1981.
+124. Campbell, T. C. Three lectures on environmental
carcinogenesis, cancer risk assessment and diet and cancer.
Annual Midwest Seminar of Dental Medicine, Wisconsin,
September 14-16, 1981.
13
#125. Chen, J., Campbell, T.C., Goetchius, M.P. and Combs, G.F., Jr.
The effects of dietary selenium and vitamin E on covalent
binding of aflatoxin to chick liver cell macromolecules. Fed.
Proc. 40:3822 Abs., 1981.
#126. Faris, R.A. and Campbell, T.C. Expression of neonatal
imprinting of carcinogen metabolism in adult male rats. J.
Tox. Appl. Pharmacol. I:555 Abs., 1981.
***127. Faris, R.A. and Campbell, T.C. Permanently altered chemical
carcinogen metabolism as related to the neonatal environment.
Science 211:719-721, 1981.
#128. Mainigi, K.D. and Campbell, T.C. Change in hepatic
glutathione (GSH) levels in male and female F-344 rats treated
with low protein and dietary aflatoxin (AFB1). J. Tox. Appl.
Pharmacol. I:474 Abs., 1981.
***129. Mainigi, K.D. and Campbell, T.C. Effect of low dietary
protein and dietary aflatoxin on hepatic glutathione levels in
F-344 rats. J. Tox. Appl. Pharmacol. 59:196-203, 1981.
***130. Mainigi, K.D. and Campbell, T.C. Effect of sex differences on
subcellular distribution of aflatoxin in F-344 rats treated
with various risk-modifying factors. J. Tox. Appl. Pharmacol.
58:236-243, 1981.
#131. Prince, L.O. and Campbell, T.C. In vivo binding of aflatoxin
to rat liver chromatin proteins as influenced by sex and
dietary protein levels. Fed. Proc. 40:3476 Abs., 1981.
+132. Campbell, T.C. Nutrient toxicities: its main thesis.
Presented to Council for Responsible Nutrition
Scientific/Technical Committee. Phoenix, AZ. May 27, 1981.
+133. Appleton, B.S. and Campbell, T.C. The dietary protein level
during the promotion phase of aflatoxin B1 induced
preneoplastic hepatic lesion development overwhelms the effect
of protein on initiation. Fed. Proc. 41, 355 Abs., 1982.
***134. Appleton, B.S. and Campbell, T.C. Inhibition of aflatoxininitiated
preneoplastic liver lesions by low dietary protein.
Nutr. Cancer 3:200-206, 1982.
***135. Appleton, B.S., Goetchius M.P. and Campbell, T.C Linear doseresponse
curve for the hepatic macro-molecular binding of
aflatoxin B1 in rats at very low exposures. Cancer Res.
42:3659-3662, 1982.
#136. Appleton, B.S., Goetchius, M.P. and Campbell, T.C. Is there a
low-dose threshold for hepatic macromolecular binding of
aflatoxin B1? Toxicologist 2:91 Abs., 1982.
14
#137. Boyd, J.N., Misslbeck, N., Campbell, T.C. and Stoewsand, G.S.
Enhancement of aflatoxin B1 induced elevation of blood afetoprotein
and emergence of g-glutamyl transpeptidase hepatic
foci by dietary vegetables. Toxicologist 2:98 Abs., 1982.
#138. Boyd, J.N., Misslbeck, N., Parker, R.S. and Campbell, T.C.
Sucrose enhanced emergence of aflatoxin B1 (AFB1)-induced GGT
positive rat hepatic cell foci. Fed. Proc. 41:356 Abs., 1982.
+139. Campbell, T.C., Appleton, B.S., Casella, G. and Goetchius M.
Can Nutrition Put Cancer on Hold? Symposium on research
opportunities in diet and cancer. American Institute of
Nutrition, FASEB, New Orleans, 1982, April 18, 1982.
**140. Campbell, T.C. Nutritional modulation of carcinogenesis. In:
Molecular Interrelations of Nutrition and Cancer, Arnott, M.S.
and Van Eys, J. (eds.). Raven Press: New York, pp. 359-367,
1982.
***141. Chen, J., Goetchius, M.P., Campbell, T.C. and Combs, G.F., Jr.
Effects of dietary selenium and vitamin E on hepatic mixedfunction
oxidase activities and in vivo covalent binding of
aflatoxin B1 in rats. J. Nutr. 112:324-331, 1982.
***142. Chen, J., Goetchius, M.P., Combs, G.F., Jr. and Campbell, T.C.
The effect of dietary selenium and vitamin E on covalent
binding of aflatoxin to chick liver cell macromolecules. J.
Nutr. 112:350-355, 1982.
#143. Coleman, R.D., Root, M. and Campbell, T.C. Novel binding
properties of aflatoxin B2a and dihydrodiol to RNA and DNA.
Fed. Proc. 41:330 Abs., 1982.
*144. Grobstein, C., Cairns, J., Berliner, R., Broitman, S.,
Campbell, T.C., Gussow, J., Kolonel, L.N., Kritchevsky, D.,
Mertz, W., Miller, A.B., Prival, M.J., Slaga, T., Wattenberg,
L. Diet, Nutrition and Cancer: (Palmer, S., Project
Director). National Academy Press, Washington, D.C. 1982.
+145. Campbell, T.C. What is this about meat consumption and cancer
risk? Cornell Nutrition Conference. Syracuse, NY. 1982.
#146. Misslebeck, N., Boyd, J.N., Campbell, T.C. and Stoewsand, G.S.
Dose-related induction of plasma a-fetoprotein elevation and
emergence of g-glutamyl transpeptidase-positive hepatic foci
in rats fed aflatoxin B1. Toxicologist 2:98 Abs., 1982.
#147. Misslbeck, N., Boyd, J., and Campbell, T.C. Single dose of
aflatoxin B1 results in GGT-positive hepatic lesions in six
weeks. Fed. Proc. 41:355 Abs., 1982.
#148. Misslbeck, N., Kim, D., Barbeau, I , Campbell, T.C. and Roe,
D.A. Response to ethanol containing liquid diets in the
15
Fischer-344 (F-344) and Sprague-Dawley (SD) rat. Toxicologists
2:53 Abs., 1982
***149. Prince, L.O. and Campbell, T.C. Effects of sex difference and
dietary protein level on the binding of aflatoxin B1 to rat
liver chromatin proteins in vivo. Cancer Res. 42:5053-5059,
1982.
#150. Shimura, J., Chang, C.C., Chen, J-H., Combs, G.F. Jr.,
Campbell, T.C. and Utermohlen, V. Effect of selenium
deficiency and excess on serum immunoglobulin and complement
levels in Fischer-344 rats. Fed. Proc. 41:707 Abs., 1982.
***151. Appleton, B.S. and Campbell, T.C. Dietary protein
intervention during the postdosing phase of aflatoxin B1-
induced hepatic preneoplastic lesion development. J. Nat.
Cancer Inst. 70:547-549, 1983.
***152. Appleton, B.S. and Campbell, T.C. The effect of high and low
dietary protein on the dosing and postdosing periods of
aflatoxin B1 induced hepatic preneoplastic lesion development
in the rat. Cancer Res. 43:2150-2154, 1983.
#153. Appleton, B.S. and Campbell, T.C. The effect of dietary
protein intervention during the post-initiation development of
aflatoxin B1 induced hepatic preneoplastic lesion development.
Fed. Proc. 42:670 Abs., 1983.
**154. Boyd, J.N. and Campbell, T.C. Impact of nutrition on
detoxication. In: Biological Basis of Detoxication, Caldwell,
J. and Jakoby, W.B. (eds.). New York: Academic Press. 1983.
**155. Campbell, T.C. Mycotoxins. In: Environmental Aspects of
Cancer: The Role of Macro and Micro Components of Foods,
Wynder, E.L., Leveille, G.A., Weisburger, J.H., Livingston,
G.E. Food & Nutrition Press, Inc. Westport, CN. pp. 187-197,
1983.
***156. Faris, R.A. and Campbell, T.C. Long-term effects of neonatal
phenobarbital exposure on aflatoxin B1 disposition in adult
rats. Cancer Res. 43:2576-2583, 1983.
*157. Grobstein, C., Cairns, J., Broitman, S., Campbell, T.C.,
Gussow, J., Kolonel, L.N., Kritchevsky, D., Mertz, W., Miller,
A.B., Prival, M.J., Slaga, T., Wattenberg, L. Diet, Nutrition
and Cancer: Directions for Research: (Palmer, S., Project
Director). National Academy Press, Washington, D.C. 1983.
#158. Misslbeck, N., Davis, E., Campbell, T.C. and Roe, D.A. The
effect of ethanol on post-initiation of liver preneoplastic
lesions in rats. Fed. Proc. 42:386 Abs., 1983.
#159. O’Connor, T.P., Youngman, L.D. and Campbell, T.C. Effect of
selenium on development of L-azaserine (Aza) induced
16
preneoplastic abnormal acinar cell nodules (AACN) in rat
pancreas. Fed. Proc. 42:670 Abs., 1983.
*160. Roe, D.A. (T.C. Campbell, Organizer of conference) Diet,
Nutrition, and Cancer: From Basic Research to Policy
Implications. Alan R. Liss. New York. 1983.
**161. Campbell, T.C. A status report on diet, nutrition and cancer.
Contemporary Nutrition 9 (8), August, 1984, General Mills
Nutrition Department, Minneapolis, MN.
***162. Misslbeck, N.G., Campbell, T.C. and Roe, D.A. Effect of
ethanol consumed in combination with high and low fat diets on
the post-initiation phase of hepatocarcinogenesis in the rat.
J. Nutr. 114:2311-2323, 1984.
#163. O’Connor, T.P. and Campbell, T.C. Influence of dietary fat
and selenium on L-azaserine-induced preneoplastic abnormal
acinar cell nodule development in rat pancreas. Fed. Proc.
43:2975, Abs., 1984.
#164. O’Connor, T.P., Roebuck, B.C., Peterson, F. and Campbell, T.C.
Effect of dietary intake of menhaden oil and fish protein on
the development of L-azaserine induced preneoplastic lesions
in rat pancreas N-3 Fatty Acid Conf. Proc., Reading, Engl.,
1984.
*165. Roe, D.A. and Campbell, T.C., Editors. Drugs and Nutrients,
The Interactive Effects. Marcel Dekker, Inc., New York. 1984.
**166. Campbell, T.C. A status report on diet, nutrition and cancer.
Contemporary Nutrition 9 (8), August, 1984, General Mills
Nutrition Department, Minneapolis, MN., (Reprinted in J.
Dentistry for Children. Jan.-Feb., 1985, pp. 65-67.)
***167. Campbell, T.C. Reponse (concerning AICR), letter submitted to
Editor) J. Chron. Dis. 38:456, 1985.
#168. Chen, J., Houghton, L., Li, J., Peto, R., and Campbell, T.C.
Protein status as measured by retinol binding protein and
prealbumin and its relationship to cancer mortality in the
People’s Republic of China. Fed. Proc. 44:Abs.768, 1985.
#169. Chen, J.C., Peto, R. and Campbell, T.C. Dietary nutritional
status and cancer mortality in China. XIII Int. Cong. Nutr.
Proc., 1985.
#170. Dunaif, G.E. and Campbell, T.C. Development of aflatoxin B1
(AFB1) induced hepatic gamma-glutamyl transpeptidase positive
(GGT+) foci in rats over time. Proc. Soc. Toxicol., 1985.
xxxx
#171. Dunaif, G.E. and Campbell, T.C. Relationship between dietary
protein level and formation of hepatic g-glutamyl
transpeptidase positive (GGT+) foci in rats following
17
aflatoxin B1 (AFB1) administration. Fed. Proc. 44:1672 Abs.,
1985.
#172. O’Connor, T.P., Roebuck, B.D., and Campbell, T.C. Dietary fat
intervention during the post-initiation phase of L-Azaserineinduced
pancreatic preneoplastic lesions. Fed. Proc. 44:2088
Abs., 1985.
***173. O’Connor, T.P., Roebuck, B.D. and Campbell, T.C. Dietary
intervention during the postdosing phase of L-azaserine
induced preneoplastic lesions. J. Natl. Cancer Inst. 75:955-
957, 1985.
#174. O’Connor, T.P., Roebuck, B.D., Peterson, F., and Campbell,
T.C. Effect of dietary intake of fish oil and fish protein on
the development of L-Azaserine induced preneoplastic lesions
in rat pancreas. Fed. Proc. 44:2092 Abs., 1985.
***175. O’Connor, T.P. , Roebuck, B.D., Peterson, F. and Campbell,
T.C. Effect of dietary intake of fish oil and fish protein on
the development of L-azaserine induced preneoplastic lesions
in rat pancreas. J. Natl. Cancer Inst. 75:959-962, 1985.
**176. Misslbeck, N.G., and Campell, T.C. The role of ethanol in the
etiology of primary liver cancer. Adv. Nutr. Res. (Ed.,
Draper, H.) 7:129-153, 1985.
#177. Youngman, L., Chen, J., Liu, S., Li, J., Peto, R., and
Campbell, T.C. Trace mineral levels in human plasma and their
relationship to cancer mortality in the People’s Republic of
China. Fed. Proc. 44:1341 Abs., 1985.
#178. Campbell, T.C. Response to Richard Severson and Steven Self.
J. Chron. Dis. 38:455, 1985.
**179. Campbell, T.C. Diet as a cause of cancer: An update. Int.
Medicine Specialist 6:109-114, 1985.
+180. Campbell, T.C., Chen. J., Li, J. and Peto, R. Assays of
Cancer Risk Factors in China. Symposium on Epidemiology and
Cancer Registries in the Pacific, Kauai, Hawaii, November 20,
1986.
+181. Campbell, T.C. Dietary Guidelines to Reduce Cancer: The
Larger Perspective. Plenary speaker for Governor’s Conference
on Cancer Prevention, Albany, New York, September 11, 1986.
+182. Campbell, T.C. Food Quality as Measured by Changes in Buying
Behavior Required for Chronic Disease Risk Reduction. In:
Consumer Demands in the Marketplace: Public Policies Related
to Food Safety, Food and Agricultural Policy. Resources for
the Future. Washington, D.C., pp. 33-35. 1986..
+183. Campbell, T.C. How Reliable is Scientific Evidence Used to
Support Advertisements Based on Health Claims? Symposium on
18
Diet and Cancer: Public Health Messages in Product, Chairman,
American Institute for Cancer Research, Washington, D.C.,
September 25, 1986.
***184. Chen, J., Ohshima, H., Bartsch, H., Yang, H., Li, J.,
Campbell, T.C., Peto, R. A correlation study on urinary
excretion of N-Nitroso compounds and cancer mortality in the
People’s Republic of China: Interim Results. Proceedings of
Nitrosamine Conference, Vienna, Austria, September, 1986.
**185. Hayes, J.R. and Campbell, T.C. Food Additives and
Contaminants. In: Casarett and Doull’s Toxicology, Klaassen,
C.D., Amdur, M.D. and Doull, J. (eds.). MacMillan Pub. Co.,
N.Y., 1986.
**186. Misslbeck, N. and Campbell, T.C. The role of ethanol in the
etiology of hepatocarcinogenesis. In: Diet, Nutrition and
Cancer: A Critical Evaluation, Vol. II., Reddy, B.S. and
Cohen, L. (eds.). CRC Press, Boca Raton, Fl. 1986.
***187. Misslbeck, N.G., Roe, D.A. and Campbell, T.C. Increase in
hepatic GGT – activity following chronic ethanol intake in
combination with a high a fat diet. Biochem. Pharm. 35:399-
404, 1986.
**188. O’Connor, T.P. and Campbell, T.C. Dietary Guidelines In:
Dietary Fat and Cancer. Ip, C., Bart, D., Mettlin, C. and
Rogers, A. (eds.). Alan R. Liss, Inc., pp. 731-771, 1986.
+189. Campbell, T.C. China project overview. Workshop on China-
Cornell-Oxford project. Cornell University, Ithaca, NY.
October 26, 1987.
+190. Campbell, T.C. Diet and the epidemiology of cancer in China:
preliminary findings. Presented at International Seminar on
Nutrition, Chronic Diseases, and Health. Budapest, Hungary,
October 6, 1987.
+191. Campbell, T.C. Dietary and nutritional strategies for cancer
control. Open Forum – Cancer control revisited. Federation of
American Societies for Experimental Biology. Washington, D.C.,
March 31, 1987.
#192. Campbell, T.C. Overview of nutrition in the causation of
cancer. Proc. of Conf. for Adv. Practice and Research,
American Dietetic Association, 39: xxxx Abs., 1987.
+193. Campbell, T.C. Potential for research on nutrition and
chronic disease in The People’s Republic of China. Committee
on Diet and Health, NRC/NAS, Washington, D.C. April 7, 1987.
+194. Campbell, T.C. Quantitative and qualitative criteria for
dietary guidelines. Workshop of Committee on Diet and Health,
NRC/NAS, Washington, D.C. April 6, 1987
19
+195. Campbell, T.C. Strengths and weaknesses of hypothesis on the
nutritional etiology of cancer: a comprehensive data base in
China. Lecture given to Imperial Cancer Research Fund, London.
October 1, 1987.
#196. Dietert, R.R., Youngman, L., Golemboski, K.A., Campbell, T.C.
Immune function during the dietary suppression of
preneoplastic foci. Fed. Proc. 46:588, 1987.
***197. Dunaif, G.E. and Campbell, T.C. Dietary protein level and
aflatoxin B1 -induced preneoplastic hepatic lesions. J. Nutr.
117:1298-1302, 1987.
***198. Dunaif, G.E. and Campbell, T.C. Relative contribution of
dietary protein level and aflatoxin B1 dose in generation of
presumptive preneoplastic foci in rat liver. J. Nutr. 78:365-
369, 1987.
**199. O’Connor, T.P. and Campbell, T.C. The influence of nutrition
on carcinogenesis. Nutrition. 3:155-162, 1987.
#200. Youngman, L.D., Houghton, L.A., Campbell, T.C. Dietary
Protein manipulation of aflatoxin-induced preneoplastic lesion
development in rat liver. Fed. Proc. 46:581 Abs., 1987.
+201. Campbell, T.C. Qualitative vs. Quantitative Guidelines.
Presented to Committee on Diet and Health, National Research
Council, National Academy of Sciences Washington, D.C., April
6, 1987.
+202. Campbell, T.C. Diet and the epidemiology of cancer in China:
preliminary findings. In: Nutrition, Chronic Diseases and
Health, an Intenational Symposium (Palmer, S., organizer)
Budapest, Hungary. October 6-8, 1987.
*203. Kinlen, L., and Campbell, T.C. (editors). Advances and
prospects in clinical, epidemiological and laboratory
oncology. Cancer Surveys 6 (No. 4), 1987.
**204. O’Connor, T.P., Roebuck, B.D. and Campbell, T.C. Effect of
varying dietary omega-3:omega-6 fatty acid ratio on Lazaserine
induced preneoplastic development in rat pancreas.
Proceedings of the AOCS Short Course on Polyunsaturated Fatty
Acids and Eicosanoids, American Oil Chemists’ Society, May 14-
17, 1987. Chap. 27, pp. 238-240.
+205. Campbell, T.C. Cancer in China. The Vahouny Fiber Symposium.
Washington, DC. April 22, 1988.
***206. O’Connor, T.P. and Campbell, T.C. The contribution of animal
experiments to knowledge of the relationship between diet and
cancer risk in humans. Cancer Surveys, xxxxx, 1988.
20
***207. Campbell, T.C. and O’Connor, T.P. Scientific evidence and
explicit health claims in food advertisements. J. Nutr.
Ed.20:87-92, 1988.
***208. Campbell, T.C., Chen, J., Li, J. and Peto, R. Nutritional and
other causes of cancer in China. Mechanisms of carcinogenesis
and emerging concepts of technology. The Aspen Cancer
Conference, Aspen, Colorado, July 19-22, 1987. Toxicol.
Pathol. 16:53-102, 1988.
***209. Potischman, N., Byers, T., Houghton, L., Root, M., Campbell,
T.C. Effects of breast cancer and its treatment on blood
nutrient levels. Soc. Epidem. Res., June, 1988.
#210. Krieger, E., Youngman, L.D., and Campbell, T.C. The
modulation of aflatoxin B1(AFB1) induced preneoplastic lesions
by dietary protein and voluntary exercise in Fischer 344 rats.
FASEB J. 2:3304 Abs., 1988.
#211. Campbell, T.C. Associations of environmental and dietary
practices with causes of death in the People’s Republic of
China. FASEB J. 2:4559 Abs., 1988.
#212. Parker, R.S., Chen, J., Campbell, T.C., Boreham, J., Wang, G.,
Houghton, L., and Youngman, L. Geographical variation in
erythrocyte fatty acid composition in the PRC and its
relationship to diet and chronic disease. FASEB J. 2:4561
Abs., 1988.
#213. Potischman, N., Houghton, L., Root, M., and Campbell, T.C.
Differences in nutrient status between women with benign
breast disease and malignant breast cancer. FASEB J. 2:4568
Abs., 1988.
#214. Youngman, L.D., Houghton, L.A. and Campbell, T.C. Plasma
freeze-thaw coagulation: characterization and a method for
dispersion. FASEB J. 2:6488 Abs., 1988.
#215. Campbell, T.C. Background paper for testimony on the role of
dietary factors in the induction of chronic disease processes.
Hearings before the Committee on Governmental Affairs, United
States Senate on Role of Nutrition in Health and Disease,
March 1, 1988. U.S. Government Printing Office, pp. 26-30,
37-41.
#216. Beard, J., Campbell, T.C., and Chen, J. Iron nutriture in the
Cornell-China diet cancer survey. Am. J. Clin. Nutr. 47:771
Abs., 1988.
***217. Wang, G., Root, M.M., Ye, X., Chen, J., Campbell, T.C.
Routine assay of plasma carotenes by HPLC with an internal
standard. J. Micronutr. Anal. 5:3-14, 1989.
21
**218. Campbell, T.C. A study of diet, nutrition and disease in the
People’s Republic of China (Parts I & II). Contemporary Nutr.
14: xxx, 1989.
***219. Peto R, Boreham J, Chen J, Li J, Campbell TC, Brun T. Plasma
cholesterol, coronary heart disease and cancer. Brit Med J.
298:1249, 1989.
***220. Schulsinger, D.A., Root, M.M., Campbell, T.C. The effect of
dietary protein quality on aflatoxin B1-induced hepatic
preneoplastic lesion development. J. Natl. Cancer Inst.,
81:1241-1245, 1989.
***221. O’Connor, T.P., Roebuck, B.D., Peterson, F.J., Lokesh, B.,
Kinsella, J.E., Campbell, T.C. Effect of dietary omega-3 and
omega-6 fatty acids on development of azaserine-induced
preneoplastic lesions in rat pancreas. J. Natl. Cancer
Inst.81:858-863, 1989.
+222. Williams G ed. Symposium Overview: American Health
Foundation’s 20th Anniversary International Symposium on
Causes and Prevention of Cancer. New York City, December 11-
12 1989.
#223. Potischman, N., Byers, T., Houghton, L., Root, M., Graham, S.,
Campbell, T.C. Effects of breast cancer and its treatment on
blood nutrient levels. FASEB J. 3:751 Abs., 1989.
#224. Youngman, L.D., Houghton, L.A., Bell, R.C., Campbell, T.C.
The modulation of aflatoxin B1 (AFB1)-induced tumors by
dietary protein. FASEB J. 3:473 Abs., 1989.
+225. Campbell, T.C. Mortality rates in transition in the People’s
Republic of China. 14th International Congress of Nutrition,
(Editors, Young, K.W., Cha, L.Y., Yull, L.K., Soon, J.J.)
Seoul, Korea, August 20-25, 1989.
+226. Campbell, T.C. A plant-enriched diet and long-term health,
particularly in reference to China. In: Proceedings of the
2nd International Symposium on Horticulture and Human Health.
Contributions of Fruits and Vegetables, Alexandria, VA,
November 4, 1989.
***227. Brun, T.A., Campbell, T.C., Geissler, C.A., Fu, S.T.,
Cirrhosis of the liver and mouldy bread. Lancet; Dec. 16,
1989, pp. 1453-1454.
***228. He, Y., Campbell, T.C. Effects of carotenoids on aflatoxin
B1- induced mutagenesis in S. typhimurium TA100 and TA98.
Nutr. Cancer 13:243-254, 1990.
*229. Chen, J., Campbell, T.C., Li, J., Peto, R. Diet, lifestyle
and mortality in China. A study of characteristics of 65
Chinese counties. Joint publication of: Oxford University
22
Press, Cornell University Press and The People’s Medical
Publishing House, 1990.
***230. Chen, J., Campbell, T.C., Parpia, B., Qu, Y., Brun, T., Chen,
C. The change of disease patterns and control strategies.
Chinese J. Prev. Med. 4:291-293, 1990.
**231. Campbell, T.C., Chen, J., Brun, T., Parpia, B, Qu, Y., Chen,
C., Geissler, C. Can developing nations avoid the diseases of
affluence? The case of China. In: World Food Issues, Vol. 2,
(T.Brun & M. Latham eds.), pp. 56-63, Center for the Analysis
of World Food Issues, Program in International Agriculture,
Cornell University, Ithaca, NY. 1990.
***232. Marshall, J.R., Qu, Y., Chen, J., Parpia, B., Campbell, T.C.
Another ecologic datum: lipid intake and status and breast
cancer in the People’s Republic of China. Submitted J. Natl.
Cancer Inst., 1990. xxxxxx
***233. Fan, W., Parker, R., Parpia, B., Qu, Y., Cassano, P.,
Crawford, M., Leyton, J., Tian, J., Li, J., Chen, J.,
Campbell, T.C. Erythrocyte fatty acids, plasma lipids and
cardiovascular disease in rural China. Am. J. Clin. Nutr.,
52:1027-1036, 1990.
***234. Campbell, T.C., Brun, T., Chen, J., Feng, Z., Parpia, B.
Questioning riboflavin recommendations on the basis of a
survey in China. Am. J. Clin. Nutr.51:436-445, 1990.
#235. Brun, T.A., Chen, J., Campbell, T.C. Urinary riboflavin
excretion after a load test in rural China as a measure of
possible riboflavin deficiency. FASEB J. xxxx Abs,1990.
#236. Bell, R.C., Golemboski, K.A., Youngman, L.D., Affolter, V.,
Perrone, M.A., Dietert, R.R., Campbell, T.C. NK cell activity
and dietary protein intake in an aflatoxin B1 (AF)-induced
tumor model. FASEB J. 4:1043 Abs,1990.
#237. Houghton, L.A., Youngman, L.D., Campbell, T.C. Effect of
dietary protein quality and quantity on development of
aflatoxin B1-induced hepatic preneoplastic lesions. FASEB J.
4:1177 Abs,1990.
#238. Golemboski, K.A., Youngman, L.D., Affolter, V., Perron, M.A.,
Dietert, R.R., Campbell, T.C. NK cell activity and dietary
protein intake in an aflatoxin B1 (AF)-induced tumor model.
FASEB J. 4:1043 Abs,1990.
#239. Youngman, L.D., Campbell, T.C. Dietary protein and
development of aflatoxin B1, (AFB)-induced preneoplastic
lesions and tumors. FASEB J. 4:1041 Abs,1990.
#240. Lange, T., Root, M., Pickul, A., Groopman, J., Campbell, T.C.
Dissimilarity in aflatoxin B1 (AFB) dose-response
23
relationships between DNA adduct formation and development of
preneoplastic foci in rat liver. FASEB J. 4:1017 Abs,1990.
#241. Brun, T.A., Chen, J., Campbell, T.C. Urinary riboflavin
excretion after a load test in rural China as a measure of
possible riboflavin deficiency. FASEB J. 4:374 Abs, 1990.
***242. Potischman, N., McCulloch, C.E., Byers, T., Nemoto, T.,
Stubbe, N., Milch, R., Parker, R., Rassmussen, K.M., Root, M.,
Graham, S., Campbell, T.C. Breast cancer and dietary and
plasma concentrations of carotenoids and vitamin A. Am. J.
Clin. Nutr, 52:909-915, 1990.
***243. Campbell, T.C., Wang G., Chen J., Robertson, J., Chao, Z. and
Parpia, B. Dietary fiber intake and colon cancer mortality in
The People’s Republic of China. In: Dietary Fiber, Chemistry
Physiology and Health Effects, (Ed. Kritchevsky, D., Bonfield,
C., Anderson, W.), Plenum Press, New York, 473-480, 1990.
+244. Campbell, T.C. In the midst of a nutrition revolution.
Lecture in series “Revolutions in Science”. Ithaca College,
Ithaca, NY, Feb. 15, 1990.
***245. Campbell, T, Chen, J., Brun, T.A., Liu, C., Geissler, C.A.
Aflatoxin and primary liver cancer in The People’s Republic of
China. Lancet, 335(8698), p. 1165, May 12, 1990.
***246. Forman, D., Sitas, F., Newell, D.G., Stacey, A.R., Boreham,
J., Peto, R., Campbell, T.C., Li, J., Chen, J. Geographic
association of Helicobacter pylori antibody prevalence and
gastric cancer mortality in rural China. Int J. Cancer
46:608-611,1990.
+247. Campbell, T.C. Determinants of liver cancer in People’s
Republic of China. In: Proceedings of Conference on
“Multifactorial Etiology and Multistep Development of
Hepatocellular Carcinoma”, Kauai, Hawaii, March 20, 1990.
***248. Campbell, T.C., Chen, J., Liu, C., Li, J., Parpia, B. Nonassociation
of aflatoxin with primary liver cancer in a crosssectional
ecologic survey in the People’s Republic of China,
Cancer Research, 50:6882-6893,1990.
#249. Horio, F., Bell, R.C., Youngman, L.D., Campbell, T.C. The
relationship between thermogenic changes induced by low
protein feeding and GGT+ foci responses in animals dosed with
alfatoxin-B1. FASEB J. 4: 1177 Abs,1990.
***250. Youngman, L.D., Campbell, T.C. The sustained development of
preneoplastic lesions depends on dietary protein. In Press,
JNCI, 1990. xxxxxx
+251. Berge, P., Parpia, B., Chen, J., Peto, R., Campbell, T.C.,
Armstrong, D. Candida albicans nutritional factors and
nasopharyngeal cancer in the People’s Republic of China.
24
Poster presented at Symposium on Advances in Clinical Nurition
for the 31st Annual Meetings of the American College of
Nutrition, Albuquerque, New Mexico, October 13-15, 1990.
+252. Campbell, T.C. A rewarding collaborative biomedical research
project between the People’s Republic of China, The United
States and their associates. International Health Forum –
Building a Common Ground, Santa Cruz, California, October 16-
19, 1990.
+253. Campbell, T.C. Determinants of human liver cancer in a
comprehensive survey in China. Cancer Center Seminar,
University of Alabama at Birmingham, Birmingham, Alabama,
November 20, 1990.
+254. Campbell, T.C. Dietary protein and aflatoxin-induced liver
carcinogenesis. Nutrition Sciences Research Seminar,
University of Alabama at Birmingham, Birmingham, Alabama,
November 20, 1990.
***255. Chen J, Brun TA, Campbell TC, Li J, Geissler C, Li M. Plasma
cotinine, smoking and lung cancer in China. Lancet 335:1225-
6, May 19, 1990.
+256 Campbell, T.C. Dietary protein and liver cancer: A model for
the study of nutrition and chemical carcinogens. Nutrition
Society of India Silver Jubilee Celebrations Twenty-third
Annual Meeting, Hyderabad, India, December 3-5, 1990.
***257. Campbell, T.C., Brun, T., Chen, J., Feng, Z., Parpia, B.
Reply to C.J. Bates and D.I. Thurnham. Am. J. Clin. Nutr.
51:436-445, 1990.
***258. Potischman, N., McCulloch, C., Byers, T., Houghton, L.,
Nemoto, T., Graham, S., Campbell, T.C. Associations between
breast cancer, triglycerides and cholesterol. Nutr. Cancer
15:205-216, 1991.
+259. Chen, J. Campbell, T.C. Contrasting nutrition experiences in
the East and West: a case study of China. Proc. 6th Asian
Congress of Nutrition (Ed., Chong Y.H. et al.). The Nutrition
Society of Malaysia, Kuala Lampur, Malaysia. September 16-19,
1991. pp. 337-341.
#260. Hu, J. Zhao, X., Topley, M.P. Schwartz, R., Chen, J.,
Campbell, T.C. Urinary excretion of calcium, ammonia and
titratable acid in Chinese women consuming diets varying in
calcium and protein source. FASEB J., 5:6239 Abs., 1991.
#261. Boreham, J. Peto, Campbell, T.C. Cancer mortality in China.
Sci. Rpt. 121.39 Abs., 532, 1991. xxxxxx
+262. Novak, A., Bell, R.C., Levitsky, D.A., Campbell, T.C.
Problems in the use of TOBEC for serial determination of body
composition in rats. FASEB J. 5:3429 Abs, 1991.
25
#263. Bell, R.C., Golemboski, K.A., Dietert, R.R., Campbell, T.C.
The effects of dietary protein intake on NK cell cytotoxic
activity and cell surface antigen profiles. FASEB J. 5:6257
Abs, 1991.
..#264. Cassano, P.A., Peto, R., Chen, J., Campbell, T.C. An ecologic
study of chronic obstructive pulmonary disease in the Peoples
Republic of China. Am. J. Epidemiol. 134:756,1991.
***265. Youngman, L.D., Campbell, T.C. High protein intake promotes
the growth of hepatic preneoplastic foci in F344 rats:
Evidence that early remodeled foci retain the potential for
future growth. J. Nutr.121:1454-1461,1991.
***266. Campbell, T.C., Brun, T., Chen, J., Feng, Z., Parpia, B.
Reply to CJ Bates and DI Thurnham. Am. J. Clin. Nutrition
53:575-576 xxxx (Letters to the Editor).
#267. Hu, J., Zhao, X., Topley, M.P., Schwartz, R., Chen, J.,
Campbell, T.C. Bone density of pre- and post-menopausal
Chinese women consuming diets high, moderate or lacking in
dairy products. Am. Soc. Clin. Nutr. Abstract #45, May 2,
1991.
+268. Campbell, T.C. A consistent nutrition-cancer association
based on laboratory animal and human data. International
Symposium on Health Promotion, Session Two: Food, Nutrition
and Health, June 4, 1991.
***269. Campbell, T.C. Mortality rates in transition in the People’s
Republic of China. Proceedings of the International Symposium
on Food, Nutrition and Social Economic Development, 361-367,
1991.
#270. Zhao, X., Hu, J., Chen, X., Schwartz, R., Wen, Z., and
Campbell, T.C. Food habits and bone density in Chinese
elderly. First International Conference on Nutrition and
Aging, ILSI, Tokyo, Japan, Octobesr 28-30, 1991.
***271. Horio, F., Youngman, L.D., Bell, R.C., Campbell, T.C.
Thermogenesis, low-protein diets, and decreased development of
AFB1-induced preneoplastic foci in rat liver. Nutr. Cancer,
16:31-42,1991.
***272. Chen, J., Campbell, T.C. More meat does not mean better
health. World Health Forum (In Press), 1991.
***273. Chen, J., Campbell, T.C., Parpia, B. Diets and disease in
transition in the People’s Republic of China. Asian Congress
Proceedings (In Press), 1991. xxxxx
+274. Campbell, T.C. Diet and Heart Disease: Data from China.
First National Conference on the Elimination of Coronary Heart
Disease. Tucson, AZ, October 2, 1991.
26
+275. Campbell, T.C. Nutrition and Plant Based Diets. Canadian
Natural Health Society, Montreal Canada. October 8, 1991.
+276. Campbell, T.C. Keynote address. Central Massachusetts
Dietetic Association, Worchester, MA, October 17, 1991.
+277. Campbell, T.C. Keynote address. The American Dietetic
Association annual meeting. Dallas, TX, October 27, 1991.
+278. Campbell, T.C. Cancer and Dietary Antioxidants: A Case Study
in China. Pennington Conference. Baton Rouge, LA, October
29, 1991.
+279. Campbell, T.C. Breaking a Nutrition Paradigm. Mark Gehlar
Lecture. Salem, OR. November 14, 1991.
+280. Campbell, T.C. Correlating Eating Habits and Health: Lessons
from a Study in China. Grand Rounds Lecture. Salem, OR.
November 15, 1991.
**281. Wang, G, Robertson, J, Parpia, B, Junshi, C, Campbell, TCC.
Dietary composition of selected foods in the People’s Republic
of China. J. Food Composition Analysis 4:293-303,1991.
###282. Potischman N, Byers T, Houghton L, Root M, Nemoto T and
Campbell TC. Effects of breast cancer treatments on plasma
nutrient levels: Implications for epidemiologic studies.
xxxxx
+283. Protein intake said key to liver cancer promotion. Food Chem.
News, p. 28, April 1, 1991.
###284. Chen J, Geissler C, Parpia B and Campbell TC. Antioxidant
status and cancer mortality in China. Int. J. Epidemiology
21(3):1-11.
+285. Proceedings of New England Association for Cancer Research.
Campbell TC. Identification of new risk factors in the
etiology of liver cancer: Findings from a prospective study
in China. February 7, 1992, Rhode Island Hospital.
***286. Youngman LD, Campbell TC. The sustained development of
preneoplastic lesions depends on high protein intake. Nutr.
Cancer 18:131-142, 1992.
***287. Youngman, L.D., Campbell, T.C. Persistence and regression of
xxxx In Press, Carcinogenesis, 1992.
+288. Campbell, T.C. Diet and degenerative diseases: perspectives
from China. Proc. Int. Conference Degenerative Diseases.
Loma Linda, CA. 1992.
27
***289. Youngman LD, Campbell TC. Inhibition of aflatoxin B1-induced
gamma glutamyl transpeptidase-positive (GGT+) hepatic
preneoplastic foci and tumors by low protein diets: evidence
that altered GT+ foci indicate neoplastic potential.
Carcinogenesis, 13:1607-1613, 1992.
***290. Peto, R., Chen, J., Campbell, T.C., Li, J., Boreham, J., Feng,
Z., Youngman, L. A study of geographical correlations in
China. Geogr. Environ. Epidemiol. xxxx, 368-372, 1992.
***291. Potischman N, Byers R, Houghton L, Root M, Nemoto T, Campbell
TC. Effects of breast cancer treatments on plasma nutrient
levels: implications for epidemiologic studies. Cancer Epi.,
Biomarkers, Prev, in press, 1992. xxxxxx
***292. Youngman LD, Campbell TC. Attenuation of preneoplastic lesion
development by dietary protein intervention: Apparent
persistence and regression. Cancer Letters, in press, 1992.
xxxxx
***293. Zhengming, C, Keech A, Collins R, Slavin B, Chen J, Campbell
TC, Peto R. Prolonged infection with hepatitis B virus: a
factor contributing to the association between low blood
cholesterol and liver cancer. Brit. Med. J., in press. xxxxx
#294. Bell, R.C., Levitsky, D.A., Campbell, T.C. Enhanced energy
expenditure (thermogenesis) associated with low protein intke
does not inhibit AFB1-induced GGT+ hepatic preneoplastic foci
development Canad. Fed. Biol. Sci., presentation, Victoria,
B.C., 1992.
#295. Bell, R.C., Levitsky, D.A., Campbell, T.C. Enhanced
thermogenesis and reduced growth rates do not inhibt GGT+
hepatic preneoplastic foci development. FASEB J. 6:1395,1992.
***296. Bell RC, Levitsky DA, Campbell TC. The effects of Dfenfluramine
on the development of aflatoxin-B1 induced GGT+
hepatic foci in F344 rats. Int.J. Obesity, 17:215-221,1993.
***297. Bell, R.C., Golemboski, K.A., Dietert, R.R., Campbell, T.C.
Long term intake of a low casein diet is associated with a
higher relative NK cell cytotoxic activity in F344 rats.
Nutr. Cancer 22: 151-162, 1994.
+298. Campbell, T.C. How rich in plant matter should diets be to
reduce the risk of cancer? Bower Award Ceremony for Dr. Denis
Burkitt. Franklin Inst., Philadelphia, PA. January, 1993.
+299. Campbell, T.C. New opportunities for employing nutrition
knowledge in national development workshop. Indonesia Conf.,
1993.
***300. Campbell, T.C. Correspondence re: Y. Fujimoto et al.,
Alterations of tumor suppressor genes and allelic losses in
28
human hepatocellular carcinomas in China. Cancer Res. 54: 281-
285, 1994. Cancer Res. 54: 5022-5023,1994.
***301. Campbell, T.C. An overview of results and findings from an
ecological study of diet, lifestyle and mortality in China:
implications for an hypothesis on diet and chronic
degenerative diseases. XXXX, xxxx, 231-234, 1994.
***302. Campbell, T.C. Correspondence re: G-S. Qian, et al., A followup
study of urinary markers of aflatoxin exposure and liver
cancer risk in Shanghai, People’s Republic of China. Cancer
Epidemiol., Biomarkers & Prev., 3:3-10, 1994, and C.C. Harris,
Solving the viral-chemical puzzle of human liver
carcinogenesis. Cancer Epidemiol., Biomarkers & Prev., 3:1-2,
1994. Cancer Epidemiol., Biomarkers & Prev. 3:519-521, 1994.
***303. Bell, R.C., Lanou, A.J., Frongillo, E.A., Jr., Levitsky, D.A.,
Campbell, T.C. Accuracy and reliability of total body
electrical conductivity (TOBEC) for determining body
composition of rats in experimental studies. Physiol.
Behavior 56:767-773, 1994.
***304. Campbell, T.C. Chen, J. Diet and chronic and degenerative
diseases: a summary of results from an ecologic study in rural
China. In Western diseases. Their dietary prevention and
reversibility (Temple, NJ and Burkitt, DP). Humana Press,
Totawa, NJ, 1994, pp 67-118.
***305. Campbell, T.C. The dietary causes of degenerative diseases:
nutrients vs foods. In Western diseases. Their dietary
prevention and reversibility (Temple, NJ and Burkitt, DP).
Humana Press, Totawa, NJ, 1994, pp 119-152.
+306. Campbell, T.C. Nutritional and health consequences of
urbanization. Presented to 5th Millenium Conference on Urban
Health Challenges for the 21st Century. Washington, DC. June
22, 1994.
+307. Campbell, T.C. New Trends in Health Eating. Health Valley
Conference, Irwindale, CA. March 9, 1995
***308. Campbell, T.C., Chen, J., Brun, T., Parpia, B., Qu, Y., Chen,
C., Geissler, C. China: from diseases of poverty to diseases
of affluence. Policy implications of the epidemiological
transition. Ecol. Food Nutr. 27:133-144, 1992.
***309. Campbell, T.C. Chen, J. Diet and chronic degenerative
diseases: perspectives from China. Am. J. Clin. Nutr.
59(suppl):1153S-1161.
***310. Hu, J-F, Zhao, X-H, Parpia, B, Campbell, TC. Dietary intakes
and urinary excretion of calcium and acids: a cross-sectional
study of women in China. Am. J. Clin. Nutr. 58:398-406, 1993.
29
***311. Hu, J-H, Zhao, X-H, Jia, J-B, Parpia, B Campbell, TC. Dietary
calcium and bone density among middle-aged and elderly women
in China. Am. J. Clin. Nutr. 58:219-227, 1993.
***312. Hu, J-F, Zhao, X-H, Chen, J-S, Fitzpatrick, J, Parpia, B,
Campbell, TC. Bone density and lifestyle characteristics in
premenopausal and postmenopausal Chinese women. Osteoporosis
Intern. 4:288-297, 1994.
***313. Hu, J-F, Zhao, Parpia, B, Chen, J-S Campbell, TC. Assessment
of a modified household food weighing method in a study of
bone health in China. European J. Clin. Nutr. 48:442-452,
1994.
***314. Zhang, S., Parpia, B., Wang, G., Wang, J., Youngman, L.,
Campbell, T.C., Chen, J. Assessment of zinc nutritional status
in rural China. Asia Pacific J. Clin. Nutr.5: 191-195,1996.
#315. Geissler, C.A., Parpia, B., Chen, J.S., Campbell, T.C.
Anthropometric changes in Chinese adults 1983-1989. Presented
at Asian Congress of Nutrition, 1995 (published, 1996).
***316. Wang G, Brun T, Campbell TC, Chen J, Parpia B, Root M,
Geissler C, Li M. Vitamin A and carotenoid status in rural
China. Brit. J. Nutr., 76: 809-820, 1996.
***317. Gates, J., Parpia, B., xxx.Campbell, T.C. Evaluation of FIRI
(fasting insulin resistance index) and selected plasma
parameters associated with insulin resistance as predictors of
cardiovascular mortality in rural Chinese women. Lancet
(under review). 1996.
***318. Gates, J., Parpia, B., Campbell, T.C., Chen. J. Association of
dietary factors and selected plasma variables with sex hormone
binding globulin in rural Chinese women. Am. J. Clin. Nutr.
63:22-31, 1996.
***319. Campbell, T.C. Methods and criteria for nutritional
epidemiology–in need of repair–Guest Editorial. Nutr.
International. July, 1996.
***320. He, Y., Root, M.M., Parker, R.S., Campbell, T.C. Effects of
carotenoid-rich food extracts on the development of
preneoplastic lesions in rat liver and on in vivo and in vitro
antioxidant status. Nutr. Cancer 27:238-244, 1997.
***321. Cheng, Z., Hu, J., King, J., Jay, G., Campbell, T.C.
Inhibition of hepatocellular carcinoma development in
hepatitis B virus transfected mice by low dietary casein.
Hepatology 26:1351-1354, 1997.
***322. Hu, J., Cheng, Z., Chisari, F.V., Vu, T.H., Hoffman. A.R.,
Campbell, T.C. Repression of hepatitis B virus (HBV) transgene
and HBV-induced liver injury by low protein diet. Oncogene
15:2795-2801, 1997.
30
***323. Cheng, Z., Root, M., Pan, W.-H., Chen, J., Campbell, T.C. Use
of an improved method for analysis of urinary aflatoxin M1 in
a survey of mainland China and Taiwan. Cancer Epidemiol.
Biomarkers Prev 6:532-539, 1997.
+324. Campbell, T.C. Associations of diet and disease: a
comprehensive study of health characteristics in China.
Conference on “Social Consequences of Chinese Economic
Reform”, Harvard University Fairbank Center on East Asian
Studies, Cambridge, MA, May 23-24, 1997
***325. Root, M., Lange, T., Campbell, T.C. Dissimilarity in
aflatoxin dose-response relationships between DNA adduct
formation and development of preneoplastic foci in rat
liver.Chemico-Biological Interactions 106 (1997) 213-227.
***326. Campbell, T.C., Chen, J.C. Diet and Health Characteristics in
Rural China:Lessons Learned and Unlearned. Nutr. Today, in
press, 1998.
+327. Campbell, T.C., Parpia, B., Chen. J.C. Keynote Presentation:
assessment of nutritional Effects in epidemiological
investigations. In Third International conference on dietary
assessment methods, advances in dietary, biochemical and
statistical approaches. Arnhem, Holland, May 8, 1998.
***327. Campbell, T.C., Parpia, B, Chen, J-S. The contextual
framework surrounding the causes of coronary heart disease.
Am. J. Cardiology 82(Suppl 10B):18T-21T, 1998.
+329. Campbell, T.C. Presentation: Toward an Optimal Diet, Summit
on the Dietary Guidelines 2000. Physicians Committee for
Responsible Medicine and Georgetown University Medical Center.
September 18, 1998.
***330. Liu, B.-Q., Peto, R., Chen, Z.-M., Boreham, J., Wu. Y.-P.,
Campbell, T.C., Chen, J.-S., Li, J.Y. Tobacco hazards, in
China: proportional mortality study in one million deaths.
Brit. Med. J., in press, 1998.
***331. Campbell, T.C., Chen, J.C. Diet and Health Characteristics in
Rural China: Lessons Learned and Unlearned. Nutr. Today
34:116-123, 1999.
***332. Campbell, T.C. Critique of report on “Food, Nutrition and
prevention of cancer, a global perspective”. Nutr. Today, in
press, 1999.
***333. Campbell, T.C. Chen, J.S. Energy balance: interpretation of
data from rural China. Am. J. Clin. Nutr., in press, 1999.
***334. Root., M.M., Hu, J. Stephenson, L.S., Parker, R.S. Campbell,
T.C. Iron status of middle-aged women in five counties of
rural China. European J. Clin. Nutr. 53: 199-206, 1999.
31
***335. Root, M.M. Hu, J. Stephenson, L.S., Parker, R.S., Campbell,
T.C. Determinants of plasma retinal concentrations of middleaged
women in rural China. Nutrition 15: 101-107, 1999.
***336. Hu, J., Zhang, X., Chen, J., Peto, R., Campbell, T.C. Cassano,
P.A., Dietary vitamin C intake and lung function in rural
China. Am. J. Epidemiol. 148: 594-599, 1998.
** 337. Campbell, TC. Book review: “Why Some Like It Hot: Food, Genes
and Cultural Diversity” by Gary Paul Nabhan. Nature 431: 907-
908, 2004.
*** 338. Campbell, TC. Dietary protein, growth factors, and cancer
(letter to the editor). Am. J. Clin. Nutr. 85:1667, 2007
*** 339. Campbell, TC. Letters from the Global Literature: Unresolved
issue and responses. Response to Gardner, C.D. et al
(“Comparison of the Atkins, Zone, Ornish, and LEARN diets for
change in weight and related risk factors among overweight
premenopausal women.”) Med. Gen. Med. http://www.medscape.com.
July 2007
“New Century Nutrition”, formerly “Nutrition Advocate, Editorials:
Why China holds the key to your health, 7/95.
Are your genes hazardous to your health?, 8/95.
Diet vs. dollars, tamoxifen’s untold story, 9/95.
Soy…the rest of the story, 10/95.
Genetic seeds of disease, how to beat the odds, 11/95.
Chemical carcinogens: how safe are you?, 12/95.
Vegetarianism vs. science: building bridges over troubled waters,
1/96.
Do your need vitamin supplements?, 2/96.
New research: reversing heart disease with diet, 3/96.
RDAs: time to peel back the labels, 4/96.
Who’s mad…cows or humans?, 5/96.
Food pyramid mysteries, 6/96.
Graduate student theses supervised:
A. Doctoral Theses:
32
Gurtoo, H.L., 1968. Studies on Mechanisms Involved in the
Induction of Microsomal Benzpyrene Hydroxylase Following
Pretreatment with 3,4-Benzpyrene and Aflatoxin B1.
Portman, R.S., 1970. Aflatoxin Mode of Action as
Distinguished by Species Differences.
Misra, H.P., 1972. Effect of Aflatoxin on Pyridine Nucleotide
Activity: A Survey.
Doherty, W.P., 1973. Affect of Aflatoxin B1 on Mitochondrial
Functions.
Mgbodile, M.U.K., 1973. Microsomal Mixed Function Oxidation
Mechanisms Associated with Dietary Protein Insufficiency.
Hayes, J.R., 1973. Induction of Mixed Function Oxidase
Activity of Rat Liver Microsomes.
Belt, J.R., 1975. Effect of Metabolism of Aflatoxin on
Mitochondrial Transcription and Translation.
Allen-Hoffman, B.L. 1980. The Effect of Phenobarbital and
Diethyl Maleate on Aflatoxin B1-DNA Adduct Formation on In
Vitro Mutagenicity as Influenced by Dietary Protein Intake.
Faris, R., 1982. Effects of Postnatal Phenobarbital Exposure
and Nutritional Status on the Mixed-Function Oxidase System
and the Formation of Aflatoxin Macromolecular Adducts in Adult
Rats.
Appleton, B.S. 1983. The Effect of Dietary Protein on the
Different Stages of Aflatoxin B1 Induced Preneoplastic Liver
Lesion Development in the Rat.
Misslbeck, N. 1983. The Effects of Chronic Ethanol Ingestion
of the Development of Preneoplastic Lesions in the Liver.
Prince, L.O. 1983. Nutritional and Hormonal Factors Affecting
the Binding of Aflatoxin to Rat Liver Chromatin Proteins and
the Development of Preneoplastic Hepatic Lesions.
O’Connor, T.P. 1985 Effect of Dietary Fat, Protein and
Selenium on the Development of L-Azaserine Induced
Preneoplastic Lesions in Rat Pancreas.
Dunaif, G.E. 1985. The Kinetic Relationship between Aflatoxin
B1 Dose, Dietary Protein Level and Time of Emergence in the
Development of Preneoplastic Liver Lesions of the Rat.
Potischman, N.A. 1989. The Associations Between Breast Cancer
and Biochemical and Dietary Indicators of Nutrient Status.
33
Youngman, D.A. 1990. The Growth and Development of Aflatoxin
B1-Induced Preneoplastic Lesions, Tumors, Metastasis, and
Spontaneous Tumors as They are Influenced by Dietary Protein
Level, Type, and Intervention.
He, Y. 1990. Effects of Carotenoids and Dietary Carotenoid
Extracts on Aflatoxin B1-Induced Mutagenesis and
Hepatocarcinogenesis.
Hu, J. 1992. A Comprehensive Study of Bone Density, Dietary
Intake, and Lifestyle Characteristics in Middle Aged and
Elderly Chinese Women.
Bell, R. 1992. Potential mechanisms through which low dietary
protein intake inhibits the development of aflatoxin B1
induced hepatic foci and tumors.
Hu, Guizhou. 1998. The Relation of Antioxidant Nutrients to
Lung Function and Chronic Obstructive Pulmonary Disease.
Lin, Xu. 1998. Potential Tumor Promotion Effects of Anorectic
Drugs.
Flood, A. 1998. The Construction and Assessment of a
Simulation Model to Describe the Impact of Dietary Change on
the Epidemiologic Transition and its Consequences in China.
B. Masters Theses:
Baugher, W.L., 1968. Gossypol Detoxification by Fungi.
Vassef, A.A., 1967. Studies on a Bright Greenish-Yellow
Fluorescent Metabolite Produced by Aspergillus Flavus on
Certain Plant Materials.
Hanna, K.L., 1970. Effect of Protein Deprivation on Aflatoxin
Toxicity.
Allen-Hoffman, L., 1978. The Relationship Between Hepatic
Glutathione Levels and the Formation of Aflatoxin-
Macromolecule Adducts In Vivo as Influenced by Dietary Protein
Intake.
Rapp, J.S., 1982. The effects of a low protein diet and
polychlorinated biphenyls on rat liver microsomal cytochrome
P-450 and the polysubstrate monooxygenase.
Youngman, L. D., 1987 Recall, Memory, Persistence, and the
Sequential Modulation of Preneoplastic Lesion Development by
Dietary Protein.
(About 8-10 now underway or recently completed).
C. Graduate Student Advisory Committees (about 5 current)
34
Teaching experience:
Graduate Basic Biochemistry, 7 years (3-4 credits/year, 60-140
students/year). (1966-1973).
Principles of Chromatography (as part of two courses on
Methodology 502-509), 5.5 years, approximately 25 students/year
(1965-1971).
Biochemical Toxicology, 2 years (3 credits, 46 students/year)
(1974-1975).
Nutritional Biochemistry, 7 years (3 credits, 140-180
students/year) (1976-84) (Shared with M. Nesheim, 1980-84).
Molecular Toxicology, 3 years (2-3 credits, 20 students/year)
(1974-1981).
Nutrition for Honors Students, 3 years (1 credit, 7-10
students/yr), 1990-1992.
Various lectures in several other courses, mostly including
information on Environmental Toxicology, International Nutrition,
and Diet, Nutrition and Cancer.
Vegetarian nutrition (undergraduate) 1996-97.
Other professional activities:
A. Outside University:
Advisory Board, Physicians Committee for Responsible Medicine,
(1997-present)
Member (Ad Hoc), Research and Education Oversight Committee,
American Institute for Cancer Research (1996-present)
Co-Chair and Organizer, Asian Food Pyramid Conference, San
Francisco, CA (1995)
Co-Chair, Expert Committee on Dietary Prevention of Cancer
World-wide, World Cancer Research Fund (1994-1997)
Member, Board of Directors, Paracelsian, Inc., Ithaca, NY
(1994-present)
Editor-In-Chief, New Century Nutrition, Ithaca, NY (1995-
present)
Founding Director, PacificHealth, Inc. (1995-present)
35
Chair, Science Advisory Committee, PacificHealth, Inc. (1995-
present)
Founding Director, Biomar International, Inc. (1996-present)
Member, Grants Review Panel, World Cancer Research Fund,
London, U.K. (1994-present)
Member, International Scientific Advisory Board, Oldways
Preservation & Exchange Trust (1994-present)
Member, Health Care Costs Review Committee, American Institute
for Cancer Research (1994)
Senior Science Adviser, American Institute for Cancer
Research/World Cancer Research Fund (1983-1988, 1992-present)
Member, National Cancer Institute, Ad Hoc Consultant Group on
Dietary Guidelines (1989).
Member, American Cancer Society Scientific Advisory Committee
on Carcinogenesis and Nutrition, 1989-present.
Member, National Academy of Science, Committee on Food
Labeling, 1989-1990.
Invited Testimony on “The Role of Dietary Factors in the
Induction of Chronic Disease Processes,” U.S. Senate,
Governmental Affairs Committee, Chair: Senator John Glenn,
Washington, D.C., March 1, 1988.
Visiting Professor, Virginia Tech, (taught 3 credit course)
Summer, 1988.
Chairman, American Institute for Cancer Research Symposium on
“Diet and Cancer; Public Health Messages in Product
Advertising”, Washington, D.C., September 1986.
Organizer and Chairman of workshop on “Diet and Cancer: From
Basic Research to Policy Implications,” Ithaca, N.Y., August
1982.
Senior Science Advisor, American Institute for Cancer Research
(1983-1987)
Nominee for President, American Institute of Nutrition (FASEB)
for 1982-1983 term.
Consultant, U.S. Federal Trade Commission (1982-1985).
Member, National Academy of Science Committee on Diet,
Nutrition and Cancer (1980-1983).
Member, NIH Chemical Pathology Study Section, 1978, 1982-1984.
36
Member, Review Panel for Evaluation of Outstanding
Investigator Award, NCI. 1984.
Senior Investigator. Social Epidemiology of Cancer, Saxon
Graham, Principal Investigator, SUNY/Buffalo Medical Center.
National Cancer Institute Fellow to Chinese Academy of Medical
Sciences (1981).
Food and Drug Administration Consultant Group on Risk
Assessment (1980).
Tufts University USDA Human Nutrition Research Center,
consultant (1981).
NIH Site Visit Study Sections (chairman of several program
grant site visits, 1980-present).
NCI Workshop on Experimental Diets and Chemical Carcinogenesis
(1980).
American Institute of Nutrition Ad-Hoc Committee on Public
Nutrition Affairs, Ex Officio, 1980-present).
FASEB/LSRO Study Workshop on Nutrient Toxicities (Co-
Chairman), 1979-1980.
FASEB/LSRO Study Workshop Panel on Evaluation of Nutrient
Safety, 1979-1980.
FASEB Public Affairs Committee, AIN representative (1979-
1983).
Member, National Academy of Science Committee on Saccharin and
Food Safety Policy, Panel II, Food Safety Regulation and
Societal Impact. 1978-79.
Public Testimony on Food Safety Policy report of NAS Panel II,
U.S. House of Representatives Subcommittee on Health and the
Environment of the Committee on Interstate and Foreign
Commerce, Washington, D.C., April 11, 1979.
Public Testimony on Food Safety Policy and Saccharin Risk
Assessment, U.S. Senate, Subcommittee on Health and Science,
Washington, D.C., May 9, 1979.
Board member, Professional Standards Evaluation Board in
General Toxicology, Academy of Toxicological Sciences, 1981-
1984.
Faculty, Annual Midwest Seminar of Dental Medicine, September,
1981.
Advisory Board, Points of View, A Nutrition Report, 1977-1981.
37
Public Testimony on “Diet, Nutrition and Cancer,” New York
State Assembly Committee on Health, New York, NY, August 10,
1978.
Editorial Board, Journal of Nutrition, 1977-1981.
Editorial Board, Drug-Nutrient Interactions, 1980-1981.
Contributing Editor, Nutrition Reviews, 1977-1981.
Editorial Board, Journal of Environmental Health Sciences,
1978-1981.
Editorial Board, Journal of Toxicology and Environmental
Health Sciences, 1974-1977.
FDA/NCI Steering Committee on Mycotoxin Congress, 1976-77.
AIN Publications Management Committee, 1975-77
ASPET/AIN/FASEB Research Committee on Nutrition/Pharmacology/
Toxicology, 1972.
National Academy of Science Committee on Carcinogenesis
Testing in Drug Development, 1972.
B. VPI & SU:
University Patents Committee, 1973-1975
University Committee on International Programs, 1972-1975
Chairman, Subcommittee on Research and Development (UCIP),
1972-1975
College Research Advisory Committee, 1969
Departmental Graduate Student Committee, 1970-1974
Departmental Executive Committee, 1974-1975
Curriculum Committee, 1966-1971
International Nutrition Committee, 1972-1975
C. Cornell:
Division Council, 1975-1976
Division Curriculum Committee, 1975-1978
Faculty Search Committees, 1976-1977, 1979
Division International Nutrition Committee, 1975-1978
Chairman, Toxicology Seminar, 1976-1978, 1979
Division Building Committee
Radiation Zone Supervisor (1978-1984)
D. Seminars and lectures off campus (200+)
E. Professional consulting with several industry and government
groups (FDA; FASEB; M&M Mars, Inc.; NASA; NIH; Environ
Control; Chocolate Mfgs. Assoc.; Florida Department of Citrus;
Federal Trade Commission; General Mills, Inc., Health Valley,
Inc., Kellog Company, Inc., NuSkin, Inc., World Bank)
38
International Experience:
A. Evaluation of Aflatoxin Problem:
Haiti (on site), 1966, 1974.
Dominican Republic (on site), 1967.
Philippines (on site), 1967, 1969, 1970, 1972, 1973, 1975.
Peru, Jamaica, Brazil, Finland, Turkey (partially on site,
partially on campus).
B. Evaluation of Liver Cancer–Aflatoxin Relationship,
Philippines (1966–1978); China (1983–present).
C. Advisory capacity in organization of laboratory facilities
(Dominican Republic, Indonesia, Philippines) (USAID, UNICEF
sponsored).
D. Principal Investigator and Director, Collaborative research
program on diet and cancer survey in People’s Republic of
China (1982 – current).
E. Collaborator in research program on dietary and lifestyle
causes of disease, Republic of China (Taiwan) (1988–present).
F. Senior Science Advisor, World Cancer Research Fund (United
Kingdom, The Netherlands) (1992-present)
G. Consultant and advisor to Central European Commitee on Health
and the Environment and Physicians On-The-Don (Moscow and
Rostov, Russia) (1995)
H. Advisor to Cornell International Institute for Food and
Agriculture Development–in charge of Nutrition Programming
(Indonesia) (1993-1996)
I. Seminar Speaker and Frequent Informal Constultant to the World
Bank (1996-1998)
Personal Interests:
Family Activities
Little League Coaching
Gardening
Reading (philosophy, history)
Bicycling

Dean Ornish

Dean Michael Ornish (born July 16, 1953) is a physician and president and founder of the nonprofit Preventive Medicine Research Institute in Sausalito, California, as well as Clinical Professor of Medicine at the University of California, San Francisco.^[1]

Personal background

Ornish, a native of Dallas, Texas, is a graduate of Hillcrest High School of the Dallas Independent School District. He holds a Bachelor of Arts summa cum laude in Humanities from the University of Texas at Austin where he gave the baccalaureate address. He earned his M.D. from the Baylor College of Medicine, was a Clinical Fellow in Medicine at Harvard Medical School, and served a medical internship and residency at Massachusetts General Hospital (1981–1984).

Professional background

Ornish is known for his lifestyle-driven approach to the control of coronary artery disease (CAD) and other chronic diseases. Beginning in 1977, he directed a series of clinical research studies proving for the first time that comprehensive lifestyle changes could not only stop the progression of CAD but could actually reverse it. These lifestyle changes included a whole foods, plant-based diet,^[2] smoking cessation, moderate exercise, stress management techniques including yoga and meditation, and psychosocial support. He has acknowledged his debt to Swami Satchidananda for helping him develop this holistic perspective on preventive health.

This result was demonstrated in a randomized controlled trial known as the Lifestyle Heart Trial, with one-year data published in the Lancet in 1990, and five-year data published in the Journal of the American Medical Association, which recruited test subjects with pre-existing coronary artery disease.^[3][4] Not only did patients assigned to the above regimen fare better with respect to cardiac events than those who followed standard medical advice, their coronary atherosclerosis was somewhat reversed, as evidenced by decreased stenosis (narrowing) of the coronary arteries after one year of treatment. Most patients in the control group, by contrast, had narrower coronary arteries at the end of the trial than the start. Other doctors have claimed similar results with similar methods, for example: Caldwell Esselstyn,^[5] and K. Lance Gould.^[6]

This landmark discovery was notable because it had seemed physiologically implausible, and it suggested cheaper and safer therapies against cardiovascular disease than invasive procedures such as coronary artery bypass surgery, angioplasty, and stents.

Ornish also directed the first randomized controlled trial demonstrating that comprehensive lifestyle changes may slow, stop, or even reverse the progression of early-state prostate cancer. This study was done in collaboration with the Chairs of Urology at the time at UCSF (Peter Carroll) and Memorial Sloan-Kettering Cancer Center (William Fair).^[7]

In 2008, he published research in collaboration with Elizabeth Blackburn showing that comprehensive lifestyle changes affect gene expression in only three months, turning on disease-preventing genes and turning off genes that promote cancer and heart disease and increasing telomerase enzyme that lengthens telomeres, the ends of chromosomes which control ageing.^[8]

He is the author of six best-selling books, including Dr. Dean Ornish’s Program for Reversing Heart Disease; Eat More, Weigh Less; Love & Survival and his most recent book The Spectrum.

He has been a physician consultant to former President Bill Clinton since 1993, when Ornish was first asked by Hillary Rodham Clinton to consult with the chefs at The White House, Camp David, and Air Force One to cook more healthfully. In 2010, after the former President’s cardiac bypass grafts became clogged, Ornish met with him and encouraged him to follow a mostly plant-based diet, because moderate changes in diet were not sufficient to stop the progression of his heart disease, and he agreed.^[9] In contrast to Esselstyn, Ornish recommends the consumption of fish oil supplements and does not follow a strict vegetarian diet, allowing for the consumption of occasional animal products.^[10]

Ornish has written a monthly column for Newsweek and Reader’s Digest magazines and is currently the Medical Editor of The Huffington Post. A one-hour documentary of his work was broadcast on the PBS science series NOVA. In addition to being featured on Bill Moyers’ PBS series Healing & The Mind, his work is featured in a documentary film Escape Fire: The Fight to Rescue American Healthcare about transforming the future of healthcare with patient-centered, integrative medicine.

Accolades

Ornish is a member of the boards of directors of the San Francisco Food Bank and the J. Craig Venter Institute. Additionally, he is a member of the boards of directors of the U.S. United Nations High Commission for Refugees and the Quincy Jones Foundation. He is an advisory board member of HealthCorps. He was appointed to The White House Commission on Complementary and Alternative Medicine Policy and elected to the California Academy of Medicine.

He chaired the Google Health Advisory Council from 2007 through 2009.

He has received several awards, including the 1994 Outstanding Young Alumnus Award from the University of Texas, Austin; the University of California, Berkeley, “National Public Health Hero” award; the Jan J. Kellermann Memorial Award for distinguished contribution in the field of cardiovascular disease prevention from the International Academy of Cardiology; a Presidential Citation from the American Psychological Association; the Beckmann Medal from the German Society for Prevention and Rehabilitation of Cardiovascular Diseases; the “Pioneer in Integrative Medicine” award from California Pacific Medical Center; the Stanley Wallach Lectureship Award from the American College of Nutrition; the Golden Plate Award from the American Academy of Achievement; the Linus Pauling Award from the Institute for Functional Medicine; the Glenn Foundation Award for Research in Aging; the Bravewell Collaborative Pioneer of Integrative Medicine award; and the Sheila Kar Health Foundation Humanitarian Award from Cedars-Sinai Medical Center (Los Angeles).

He regularly gives keynote speeches on his findings, and has spoken at the White House, the Google Zeitgeist conference, as well as the Institute of Medicine’s first Summit on Integrative Medicine at the National Academy of Sciences.

Ornish was recognized as “one of the most interesting people of 1996” by People magazine; selected as one of the “TIME 100” in integrative medicine; honored as “one of the 125 most extraordinary University of Texas alumni in the past 125 years;” chosen by LIFE magazine as “one of the fifty most influential members of his generation;” and by Forbes magazine as “one of the seven most powerful teachers in the world.”

Published works

This article lacks ISBNs for the books listed in it. Please make it easier to conduct research by listing ISBNs. If the {{Cite book}} or {{citation}} templates are in use, you may add ISBNs automatically, or discuss this issue on the talk page. (May 2012)

Books and monographs

• Ornish, D. Dr. Dean Ornish’s Program for Reversing Heart Disease, New York: Random House, 1990; Ballantine Books, 1992.^[11]
• Ornish D. Eat More, Weigh Less. New York: HarperCollins Publishers, 1993.^[12]
• Ornish D. Everyday Cooking with Dr. Dean Ornish. New York: HarperCollins Publishers, 1996.^[13]
• Ornish D. Love & Survival: The Scientific Basis for the Healing Power of Intimacy. New York: HarperCollins, 1998.^[14]
• Ornish D. The Spectrum. New York: Ballantine Books, 2008.^[15]
• Billings J, Scherwitz L, Sullivan R, Ornish D. Group support therapy in the Lifestyle Heart Trial. In: Scheidt S, Allan R, eds. Heart and Mind: The Emergence of Cardiac Psychology. Washington, DC: American Psychological Association; 1996:233-253.^[16]
• Ornish D, Hart J. Intensive Risk Factor Modification. In: Hennekens C, Manson J, eds. Clinical Trials in Cardiovascular Disease. Boston: W.B. Saunders, 1998 (companion to Heart Disease, the Braunwald standard cardiology textbook).

• Ornish D. “Intensive Lifestyle Changes in Management of Coronary Heart Disease. In: Braunwald E. Harrison’s Advances in Cardiology. New York: McGraw Hill, 2002.^[17]
• Ornish D. “The cost-effectiveness of consumer-driven lifestyle changes in the treatment of cardiac disease.” In: Herzlinger RE. Consumer-Driven Health Care. San Francisco: Wiley & Sons, 2004.^[18]
• Scher B, Guarneri EM, Hart JA, Ornish D. Multiple Risk Factor Intervention Trials. In: Manson J, Buring JE, Ridker PM, Gaziano JM, eds. Clinical Trials in Cardiovascular Disease, Second Edition. Boston: W.B. Saunders, 2004 (companion to Heart Disease, the Braunwald standard cardiology textbook).
• Ornish D. “Our Genes Are Not Our Fate.” In: Brockman J. This Will Change Everything. New York: HarperCollins, 2010.^[19]
• Moyers, Bill. “Changing Life Habits: A Conversation with Dean Ornish.” In: Healing and the Mind. New York: Doubleday, 1993.^[20]

Original reports

• Ornish DM, Gotto AM, Miller RR, et al. Effects of a vegetarian diet and selected yoga techniques in the treatment of coronary heart disease. Clinical Research. 1979;27:720A.^[21]
• Ornish DM, Scherwitz LW, Doody RS, Kesten D, McLanahan SM, Brown SE, DePuey G, Sonnemaker R, Haynes C, Lester J, McAllister GK, Hall RJ, Burdine JA, Gotto AM. Effects of stress management training and dietary changes in treating ischemic heart disease. JAMA. 1983;249:54-59.^[22]
• Ornish DM, Brown SE, Scherwitz LW, et al. Can lifestyle changes reverse coronary atherosclerosis? The Lifestyle Heart Trial. The Lancet. 1990; 336:129-133. (Reprinted in Yearbook of Medicine and Yearbook of Cardiology (New York: C.V. Mosby, 1991).^[23]
• Gould KL, Ornish D, Scherwitz L, Stuart Y, Buchi M, Billings J, Armstrong W, Ports T, Scherwitz L. Changes in myocardial perfusion abnormalities by positron emission tomography after long-term, intense risk factor modification. JAMA. 1995;274:894-901.^[24]
• Ornish D, Scherwitz L, Billings J, Brown SE, Gould KL, Merritt TA, Sparler S, Armstrong WT, Ports TA, Kirkeeide RL, Hogeboom C, Brand RJ. Intensive lifestyle changes for reversal of coronary heart disease Five-year follow-up of the Lifestyle Heart Trial. JAMA. 1998;280:2001-2007.^[25]
• Ornish D. Avoiding Revascularization with Lifestyle Changes: The Multicenter Lifestyle Demonstration Project. American Journal of Cardiology. 1998;82:72T-76T.^[26]
• Ornish DM, Weidner G, Fair WR, Marlin R, Pettengill EB, Raisin CJ, Dunn-Emke S, Crutchfield L, Jacobs NF, Barnard RJ, Aronson WJ, McCormac P, McKnight DJ, Fein JD, Dnistrian AM, Weinstein J, Ngo TH, Mendell NR, Carroll PR. Intensive lifestyle changes may affect the progression of prostate cancer. Journal of Urology. 2005;174:1065-1070.^[27]
• Ornish D, Magbanua MJM, Weidner G, Weinberg V, Kemp C, Green C, et al. Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention. Proc Nat Acad Sci USA 2008; 105: 8369-8374.^[28]
• Ornish D, Lin J, Daubenmier J, Weidner G, Epel E, Kemp C, Magbanua MJM, Marlin R, Yglecias L, Carroll P, Blackburn E. Increased telomerase activity and comprehensive lifestyle changes: a pilot study. The Lancet Oncology. 2008; 9: 1048–57.^[8]
• Dod HS, Bhardwaj R, Sajja V, Weidner G, Hobbs GR, Konat GW, Manivannan S, Gharib W, Warden BE, Nanda NC, Beto RJ, Ornish D, Jain AC. Effect of intensive lifestyle changes on endothelial function and on inflammatory markers of atherosclerosis. Am J Cardiol. 2010 Feb 1;105(3):362-7.^[29]
• Silberman A, Banthia R, Estay IS, Kemp C, Studley J, Hareras D, Ornish D. The effectiveness and efficacy of an intensive cardiac rehabilitation program in 24 sites. Am J Health Promot. 2010;24[4]:260–266.^[30]